| 1 BackgroundIt refers to the lumbar disc herniation lumbar disc degeneration based on the rupture of the annulus and then highlight the nucleus pulposus and oppression nerve root irritation caused by a series of signs and symptoms of the disease, one of the most common clinical disorders, orthopedic, especially common spine family disease, is one of the important causes of low back pain,10%-15% of patients with low back pain clinic at approximately 25%-40% of low back pain orthopedic hospitalized patients.Treatment of lumbar disc herniation lot. currently divided into non-surgical treatment and surgical treatment. Scholars generally believe that the current 80% to 90% of lumbar disc herniation in patients with early-onset non-surgical treatment can eliminate the symptoms. Non-surgical therapy is the basic treatment of lumbar disc herniation, most patients can be subjected to non-surgical therapy to relieve symptoms or cure, the purpose is to make the non-surgical treatment of lumbar disc portion and the irritated nerve root inflammatory edema subsided accelerated, thereby reduce or alleviate nerve root irritation and oppression. Getting a healthy waist pill Guangzhou Baiyun Mountain Chen Li Ji pharmaceutical developed the production of proprietary Chinese medicines, which consists Woodwardia, laevigata suberectstem pull extremely heavy, black tiger, cattle vigorously, Ligustrum lucidum, mistletoe, dodder,Corydalis, two needles, frankincense and myrrh 13 taste of Chinese herbal medicines, of which pull extremely heavy, black tiger, great cattle, two needles Lingnan unique authentic ingredients, Fang Golden Woodwardia play strong waist and knee, liver and kidney, remove rheumatism effect. King and medicine. Black Tiger Xin Wen, qi stasis, pain network; mistletoe liver or kidney, rheumatism; Millettia blood Huoxuetongluo:daughter pull Qufengchushi; cattle vigorously Shujin; laevigata Kidney Gujing:more than a total of Chen medicine. Ligustrum lucidum. Dodder kidney tonic; Nitidum Qufengtongluo. wins wet pain; fumarate,frankincense, myrrh play together stasis analgesic effect for the drug Satsukai. More rigorous drug compatibility to play together replenishing liver and kidney, strong bones and muscles, Qufengchushi active analgesic effect. Liver and kidney deficiency syndrome patients belong, rheumatism stasis syndrome may use treatment. 2ObjectiveThrough multi-center, randomized, controlled study was getting a healthy waist pill on liver and kidney deficiency lumbar disc herniation, rheumatism stasis clinical efficacy and safety.3 Research MethodsUsing randomization assigned 110 patients with lumbar disc herniation in patients with a 3:1 ratio divided into experimental group 82 patients in the control group of 28 cases, shared by five hospitals, double-blind double-dummy, positive controls, multi-center clinical research trials, the experimental group were given pills and getting a healthy waist waist Bi capsule analog therapy, the control group received spinal paralysis capsule and getting a healthy waist pill analog therapy, a course of 4 weeks,4 weeks TCM symptom rating scale, a visual analog scale (VAS), Oswestry Disability index questionnaire (ODI) score and JOA scales as indicators of clinical efficacy, before enrollment,2 weeks±2 days post-treatment and post-treatment day 3+4 visit viewpoints record observed indicators, data SPSS 19.0 statistical software, count data with respect to the number of cases, percentage description, chi-square test, ranked data using Wilcoxon rank sum test; measurement data with X±S said that for normal distribution of data between groups using two independent samples t-test, paired t test in the group, who do not obey the normal distribution of data using the Wilcoxon rank sum test, P<0.05 considered statistically significant.4 Results4.1 Into the group before baselineIn this study,110 Patients with lumbar disc herniation,82 cases of the experimental group,41 men,41 female, mean age 49.87±10.00 years, the average duration of 32.38 ±25.40 months. The control group,28 Patients,13 males and 15 females, mean age 50.14±11.70 years, the average duration of 30.79±28.62 months. Two groups in gender, age no significant difference (P> 0.05), the same basic conditions, comparable. Two groups of patients before enrollment course, TCM symptom score, VAS, ODI and JOA score was no significant difference (P> 0.05), described two groups of patients enrolled in the same condition, comparable.4.2 Evaluation of TCM symptom scoreTCM symptom score before treatment in the experimental group and the control group X±S was 13.68±3.78 and 13.11 ±4.54, after 4 weeks of treatment groups X ±S were 6.59±3.90 and 6.29±2.89. before and after treatment in the two groups statistically Learn the difference (P<0.05). described the two drugs on patients with lumbar disc herniation treatment effect; no significant difference (P between the two groups of patients after treatment> 0.05). indicating that the two drugs to improve the situation of the patients did not difference, that the drug has the same effect on the treatment of this disease. Also compare the individual has no symptoms after 4 weeks of treatment for both drugs TCM symptom score table significant difference (P> 0.05).4.3VAS Rating EvaluationVAS scores before treatment in the experimental group and the control group X ±S respectively 5.55±1.62 and 5.29±1.76, after 2 weeks of treatment groups X±S were 4.28±1.50 and 4.14±1.56, after 4 weeks of treatment groups X±S were 2.93 ±1.36 and 2.86±.43, was observed in two segments representing the two groups before treatment after treatment VAS scores were statistically significant (P<0.05), described the two drugs on pain in Patients with lumbar disc herniation were therapeutic effect; no segment between two groups of Patients after treatment group VAS score significantly different (P> 0.05), description of the improvement of the two drugs in patients with pain, there is no difference, that is the same for the drug treatment of this disease.4.4JOA Rating EvaluationAfter treatment, two weeks, two groups in total effective rate was 51.22% and 42.86%. respectively; the two groups after 4 weeks of treatment, the total effective rate was 74.39% and 71.43%, respectively, for 2 weeks and 4 weeks, respectively, statistics groups difference in efficacy between patients, there was no statistically significant (P> 0.05), description of the two drugs in patients with signs of improvement in physical function in the same situation.4.5ODI Rating EvaluationODI score before treatment in the experimental group and the control group X± S was 16.74±7.74 and 15.96±.27, after 2 weeks of treatment X±S groups were 12.71±7.49 and 11.61±.58, after 4 weeks of treatment groups X±S They were 7.49±.97 and 7.89±.32, paragraph two points within the two groups after treatment than before treatment comparison were statistically significant(P<0.05), described the two drugs on patients with lumbar disc herniation daily activities have therapeutic effect; no significant difference (P> 0.05) between the two segments point two patients after treatment, indicating that the two drugs interact daily improvement of the patients did not differ, the same two drugs for treatment of this disease.4.6 Adverse reactionsNo correlation was found between adverse events with both drugs.5 ConclusionComparison within the group before and after treatment, the two drugs can significantly improve the patient’s pain, physical function and daily activities, there are statistically significant, indicating that the two drugs on lumbar disc herniation patients had clinical efficacy. Segment between two points on the group of the two drugs in patients with lumbar disc herniation pain, improve the efficacy of the same limb function and activities of daily living, not statistically significant. Two groups of patients were not found associated w ith both drugs adverse reactions. |
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