Risk Factors For Osteoporotic Vertebral Fracture In Postmenopausal Women

Objective Analysis of the correlation between age, height, weight, body mass index, hip bone density, static balance ability and osteoporotic vertebral fracture in postmenopausal women.Methods A retrospective analysis of the clinical data of postmenopausal women who first examined and treated in our hospital’s department of orthopedics from 2012.01 to 2015.06. Age, height, weight and hip (total hip and femoral neck)bone mineral density(BMD), falling index (FI) of theirs were collected. Through X ray of thoracolumbar lateral, we can evaluate the vertebral changes, and the spinal deformity index(SDI) is calculated to reflect the general situation of vertebral fracture. The clinical basic information were comparative analysised by divided into vertebral fracture group and non vertebral fracture group.Spearman test was used to analyze the correlation between SDI with age, height, weight, body mass index (BMI),hip BMD and FI. Further linear regression analysis was also used.Results 213 cases were enrolled, of which 114 patients with osteoporotic vertebral fractures (53.52%), while the other 99 cases are not with osteoporotic vertebral fractures (46.49%).There are 278 vertebral bodies involved, of which the rates of top 5 were followed by L1 (51,18.35%), T12 (48,17.27%), T11(45,16.19%), L4(29,10.43%), T7(28,10.07%).Based on the BMD of hip, in the osteoporotic vertebral fracture group there were 50 cases (43.86%) could be diagnosed as osteoporosis and the other 63 cases (56.14%) are in the stage of bone mass reduction, while only 23 cases could be diagnosed as osteoporosis in the non vertebral osteoporotic fracture group (23.23%) and the other 56 cases (56.57%) are in the stage of bone mass reduction. Vertebral fracture group has higher age, lower height and lower total hip and femoral neck bone mineral density, and the difference was statistically significant (P<0.001),while there were no differences in weight and body mass index between the two groups.Age, height, BMI, total hip bone density, femoral neck bone mineral density, FI and SDI were significantly correlated, and their R values were 0.361,-0.334,0.179,-0.409,-0.364,0.216, P<0.001. Further linear regression analysis show that the standardized regression coefficients were 0.303,-0.390,0.211,-0.419,-0.368, 0.242.Conclusions Decreased of hip BMD, increased of age,lower height and higher fall risk were the risk factors of osteoporotic vertebral fractures,and there was a high degree of consistency between the degree of hip bone mineral density loss, increased of age, fall risk rise with the severity of vertebral fracture.