| Objective:To observe and compare the distribution characteristics of common risk factors between youth cerebral infarction and senile cerebral infarction. At the same time, to compare the distribution differences and similarities in the same cause types, the same lesion sites and sizes between the two groups. And to further study the relationship of correlation and influence among common risk factors, etiology and location. Methods:80 young patients with new cerebral infarction are selected as experimental group. At the same time, 80 old patients with new cerebral infarction are selected as control group. Completing the auxiliary examinations and analyzing the clinical datas of the two groups are needed. The next is to discribe the distribution of the common risk factors, etiology, impared ability of daily living and location between the two groups. The method of Rank correlation analysis of Spearman is used to study the correlation among common risk factors, cause types and location. Multivariate linear regression was used to find out the risk factors of the location and the size. Besides, to recognize whether there are differences between the two groups in risk fa ctors, location, size and other aspects, we use the T test for the count data and the chi square test for the grade data. Results:(1) The incidence of high homocysteine in the two groups are very high. And the youth group is higher than the old group. At the same time, the two levels of 11-15 and 0-10 are consistent in the young group,while the old group more distributes in the level of 11-15.(2) The NIHSS score:the proportion of 0-4 points in the youth group is larger than the old group,while the proportion of 5-15 points in this group is smaller than the other group. The proportions of 16 points and above are both very small.(3) The ADL score: the youth group scores at two extremes, while the old group scores evenly.(4) The TOAST type: Young group with small vessel disease type is in the majority, while with big atherosclerosis type and the uncertained cause type live in the second place. Old group with big atherosclerosis type is in the majority, while with small vessel disease type lives in the second place.(5) In the two groups, only the internal carotid artery system involved are both the most common, and the two systems at the same time involved are in the next. The most vulnerable locations for the two groups are slightly different.(6) The common risk factors in the two groups are not statistically related to the TOAST classification,but there is a statistical correlation with the location of the disease. As to the correlation between TOAST classification and the location of the disease, there is not statistical correlation in youth group,while there is statistical correlation in old group.(7) Common risk factors on the involvement of specific lesions or not have different levels of impact. And there is a quantitative dependence relationship.(8) There is no significant difference between the two groups on the size of the same affected area. Conclusion:(1) Homocysteine levels are mostly concentrated in the 11-15 for the elderly patients. It suggests that there is a greater risk of a higher level of homocysteine in old patients. And this level is not conducive to the recovery of cerebral infarction so as to affect the prognosis.(2) Elderly patients in the parietal lobe involvement accounted for a considerable proportion, while young patients with parietal involvement is less, which is the outstanding characteristics of the old.(3) The risk factors of elderly patients can be controlled to the maximum extent. And the risk factors of young patients are more difficult to control. The extent of the damage to the nerve function of young patients is small, and the prognosis is better. Young patients with self compensatory ability is better than the elderly. |
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