The Application Value Of New Ultrasonic Technology In Papillarythyroid Microcarcinoma Diagnoses

Objective: To investigate the clinical value in the diagnosis of Papillary Thyroid Microcarcinoma(PTMC), the specific imaging characteristics of contrast-enhanced ultrasound and ultrasound elastography had been compared.Methods: We retrospectively analyzed clinical datas of 69 patients with thyroid nodules which diameter was less than 1.0 centimeters. And all these patients were adimited in the Department of General Surgery of the First Affiliated Hospital of Chongqing Medical University during June, 2015 to February, 2016. There were 107 thyroid nodules in all of those patients. All nodules were confirmed by intraoperative and pathological examination. By consulting the hospital record department, elephoning follow-up and consulting electronic medical record system retrieval, we collected the required informations, and analyzed those informations carefully before transverse analasis according to age, gender, the mass size, the new technology of ultrasonic image information obtained(including contrast-enhanced ultrasound and ultrasound elastography imaging), pathological results, and so on. Statistical data-processing was conducted by SPSS statistical software, version 18.0. Qualitative data was analyzed by chi-square test, A p value less than 0.05 was considered to be statistically significant. According to the ultrasonic imaging characteristics of the new technology(CEUS and UE), We analyzed the datas and compared the important parameters in benign and malignant small thyroid nodules respectively in the two groups. And a statistical principle was used to calculate the sensitivity, specificity, accuracy, positive predictive value and negative predictive value, aiming to find the significant difference in selected indicators by comparing with result of biopsy, then screen out the diagnostic value related to PTMC in main parameters.Results: In total, 69 patients exhibiting a total number of 107 small thyroid nodules, among them, 75 malignant nodules of thyroid papillary carcinoma were verified by intraoperative and pathological examination, And 32 nodules were diagnosed as benign lesions, of which 26 as nodular goiter, 3 as the thyroid papillary tumor, 1 case of old blood clot and 1 was hyperplastic nodule with calcification. There were some factors statistically significant(P < 0.05) in the thyroid nodules detection rate difference, such as homogeneous enhancement, vanish early, rule edge enhancement, enhanced intensity, UE scores(see table 1). The diagnosis sensitivity and specificity of the new technology(CEUS and UE) in thyroid papillary carcinoma were 84.00%, 68.75% and 93.33% 90.63%; Combining CEUS and UE, the diagnostic sensitivity and specificity had risen to 96.00% and 96.88% respectively, which had been improved significantly when compared to these by applying the two means independently.Conclusion:(1) The new technology of sonographic has a reliable value for clinical diagnosis of PTMC.(2) Combining of CEUS and UE, can improve the diagnostic sensitivity and accuracy of PTMC.