Analysis Of The Curative Effect Of Two Different Surgical Methods In The Treatment Of Pterygium

Purpose: This study respectively using autologous corneal limbus stem cell transplantation and preserved amniotic membrane transplantation in the treatment of pterygium, observe the clinical effects of their differences, and to explore surgical therapy for the treatment of pterygium.Methods: Choose patients between September 2013 and December 2014 in Department of Ophthalmology, the First Affiliated Hospital of Chongqing Medical University, eye diagnosis of pterygium and admitted patients a total of 93 cases(93 eyes), age between 25 to 80 years old. According to the different methods of surgery were randomly divided into it A, B two groups. For pterygium excision with autologous limbal stem cell transplantation cases belong to A group of 50 cases(50 eyes),Use cases of pterygium excision combined preserved amniotic membrane transplantation in 43 patients(43 eyes) with group B. For A, B two groups of patients for at least 12 months of follow-up, observe and record A, B two groups of postoperative corneal epithelial healing of at least 2 weeks and eye surgery within 1 year of recurrence of pterygium, the results and data are finally collectted and statistically analyzed.Results: A group of postoperative corneal wound healing time was(6.74 + 1.89) days,B group of postoperative corneal wound healing time was(12.23 + 5.03) days,The repair time of corneal epithelium in A group was shorter than that of group B;A group of 50 cases(50 eyes) in 2 cases(2 eyes) with A relapse, the recurrence rate was 4%. Group B 43 eyes of 43 patients with 8 cases(8 eyes) with recurrence, the recurrence rate of 18.6%,group A recurrence rate is lower than group B. Differences in the efficacy of two groups was statistically significant(P < 0.05).Conclusions: In the treatment of pterygium, autograft limbal stem cell transplantation and preserved amniotic membrane technique has achieved good clinical effect. Autologous corneal limbus stem cell transplantation is more advantageous to promote corneal wound repair and reduce the recurrence of useful, therefore deserves further clinical popularization and application.