1. The Distribution Of Glycine Receptors In Multiple Brain Regions Verified By Electrophysiology 2. Effects Of Blue Light Irradiation On Learning And Memory Ability Of Developing Mice

1. The distribution of glycine receptors in multiple brain regions verified by electrophysiologyGlycine is one of the most important inhibitory neurotransmitters in the nervous system and plays an important role in the regulation of nervous system function.Glycine receptors are abundantly distributed in the spinal cord and brainstem, but are also distributed in the upper brain regions. Modern researchers confirmed the distribution of glycine receptors by isotope labeling, in situ hybridization and other methods. But for the question that glycine receptor is specifically distributed in the postsynaptic, presynaptic, or synaptic, and there is not a clear answer. In this study,the brain, amygdala, PAG, Pnc and brain stem, which are closely related to the glycine receptor, were explored. The study found that in the amygdala, glycine receptors in the presynaptic, synaptic, postsynaptic are distributed. The EC50 of the glycine receptor of the amygdala is larger than the EC50 of the glycine receptor in the brainstem. In PAG and Pnc, glycine receptors are distributed both in presynaptic and postsynaptic.2. Effects of blue light irradiation on learning and memory ability of developing miceWhen people mention the sun, they will think of happy. When mood depressed, go outside for sunshine, and you will immediately feel the difference. Scientific research shows that sunshine can affect cognitive behavior, reduce depressive symptoms,promote bone development. How does the sunshine affect learning and learning ability? In this subject, because the blue light carried by the strong energy, so we choose the blue light not natural light. Of course, the energy of ultraviolet light is stronger, but UV will damage the skin. Experiments show that blue light on young mice make learning and memory ability improve. Blue light has no effect on the learning and memory ability of adult mice. Electrophysiological experiments showed that the amplitude of mEPSC in hippocampus of mice developed under blue light was changed. And the size and release of synaptic vesicles were significantly increased.