Preparation And Luminescent Properties Of Yb³⁺?Ho³⁺ Doped Nano-fluorapatite

Rare-earth doped nano-luminescent material is a kind of material with unique physical and chemical properties.It plays an important role in biomarker tracing,cancer therapy,biological imaging and drug carrier.Yb³⁺?Ho³⁺ doped nano-fluorapatite(FA:Yb³⁺?Ho³⁺)were prepared successfully by hydrothermal method.The effect of reaction parameters on FA:Yb³⁺?Ho³⁺ was studied.The details are as following:?1?The reaction time and reaction temperature were adjusted.The results showed that when the reaction time was 16 h,the reaction temperature reached 160 ?or over the temperature and the reaction temperature reached 160?,the reaction time was 16 h or over the time,the Yb³⁺?Ho³⁺ doped nano-fluorapatite nanoparticles form rod-like structures with uniform size.?2?The rare earth Yb³⁺ ions and Ho³⁺ ions were adjusted.The results showed that by adjusting the doped proportion of the rare earth Yb³⁺ ions and Ho³⁺ ions,upconversion luminescence efficiency of the material has greatly improved.When the ratio of Ho³⁺ ions unchanged,the strongest emitting of FA:Yb³⁺?Ho³⁺ nanomaterials is when the doped proportion of the rare earth Yb³⁺ ions reach to 60%.When the ratio of Yb³⁺ ions unchanged,the strongest emitting of FA: Yb³⁺?Ho³⁺ nanomaterials is when the doped proportion of the rare earth Ho³⁺ ions reach to 3%.Thus,this kind of FA: Yb³⁺?Ho³⁺ nanomaterials has good upconversion luminescence properties can provide favorable conditions in cell markers and imaging.It is expected to promote their wider application in the biomedical field.