Study On One-electron Oxidation Mediated Dehydrogenative Coupling Reaction

This thesis is divided into two parts: the first part summarizes the researchprogress of N-aryl tetrahydroisoquinolines oxidative coupling reaction. The secondpart for the study of the reaction, include triarylaminium salt initiated aerobic doublefriedel–crafts reaction of glycine derivatives with indoles; copper(I) chloride-catalyzed aerobic oxidative arylation of glycine ester and amide derivatives; andaerobic oxidative coupling of N-aryl tetrahydroisoquinolines.1. Tris(4-bromophenyl)aminium hexachloroantimonate (TBPA+.) could efficientlyinduce the double Friedel-Crafts reaction of glycine derivatives with indoles underaerobic conditions, producing a series of BIMs.2. Copper (I) chloride could efficiently induce the oxidative coupling reaction ofglycine derivatives with indoles under aerobic conditions, constructing new C-Cbond.3. Tris(4-bromophenyl)aminium hexachloroantimonate (TBPA+.) could efficientlyinduce the oxidative coupling reaction of N-aryl tetrahydroisoquinolines underaerobic conditions, constructing new C-C and C-P bond.