Preparation And Application Of Zwitterionic Sulfobetaine Polymer Hydrogels

Hydrogel is a kind of polymer material with hydrophilic groups and porous structure, which can swelling but never dissolve. Take advantage of the properties of hydrophilic, swelling in water, stimuli-response and so on, it can be applied in many different research fields such as biosensor, artificial skeleton, catalyst support, drug delivery system et.al.The thesis consists of four chapters: the review of hydrogel; Preparation of High-strength Polyzwitterionic Liquids Hydrogel and Applied in Catalysis; The synthesis and application of P?PVIS-AA?/SA@Pd@Ag hydrogel; Thermo-responsive hydrogel of P?NPA? used in controlled drug release, respectively.Chapter?:The reviewThe property, preparation, classification and application of hydrogel were reviewed in this chapter.Chapter?: Preparation of A Novel High-strength Polyzwitterionic Liquids Hydrogel and Applied in CatalysisA new polymeric hydrogel P?PVIS-AA? based on zwitterionic liquids?1-propyl-3-vinyl imidazole sulfonate??PVIS? and acrylic acid?AA? was prepared by free-radical polymerization. The resulting three-dimensional?3D? networks can serve as nano-reactors for the production of small size and highly stable palladium nanoparticles by in situ reduction of PdCl₆^2- with sodium borohydride?NaBH₄? as reducing agent. To get the enough mechanical strength, ferric(Fe³⁺) was used to form the second crosslinking. The as-prepared hybrid hydrogel(P?PVIS-AA?/Pd@Fe³⁺) was successfully confirmed by means of Fourier transform infrared?FTIR? spectroscopy, X-ray diffraction?XRD?, energy dispersive x-ray spectroscopy?EDX?, field emission scanning electron microscopy?FESEM?, an electrical universal material testing machine, transmission electron microscopy?TEM? and thermogravimetric analysis?TGA?. It was tested to catalyze the NaBH₄ reduction of 4-nitrophenol. The catalytic results indicate P?PVIS-AA?/Pd@Fe³⁺ shows good catalytic effects and excellent reusability.Chapter?: The synthetic and application study of P?PVIS-AA?/SA@Pd@Ag catalystThe composite P?PVIS-AA?/SA hydrogel was prepared by free radical polymerization and further ionic crosslinks through Ca²⁺. The as-prepared composite hydrogel P?PVIS-AA?/SA was successfully confirmed by means of by SEM, FTIR, EDX and others. A large number of positive and negative charges within composite hydrogel were used to attract Ag+ and PdCl₆^2-, then to be two noble metal nanoparticles by reduction of sodium borohydride?NaBH₄? at the same time, finally to be P?PVIS-AA?/SA @Pd@ Ag. The results demonstrated that the as-prepared P?PVIS-AA?/SA @Pd@ Ag with higher stability and bigger superficial area can acceleate reaction rate in organic catalytic reaction.Chapter?: P?NPA? hydrogel with thermo-responsive controlled release of drug at different temperatureA porous of hydrogel of P?NPA?, which contains PVIS and NIPAM was prepared by Free radical polymerization. It was studied single factor variable of composition influenced swelling degree, deswelling and controlled iodine releasing from composite hydrogel. From the analysis results, that P?NPA? hydrogel has excellent thermo-responsive character, and can be regarded as excellent carrier for skin surface, such as the release of iodine in skin irritation.