Effect Of Reaction Medium On Benzylation Of Aniline

As the application of amine compounds in a wide range of this article on the synthesis of amine compounds in the media were studied.?-Fe₂O₃ was prepared by using industrial pickling waste liquid,and characterized by scanning electron microscopy?SEM?,X-ray diffraction?XRD?,transmission electron microscopy?TEM?,Fourier Transform infrared spectroscopy?FT-IR?respectively.The conversion of aniline to benzyl chloride was catalyzed by?-Fe₂O₃ under solvent-free conditions.The conversion of benzyl chloride was almost 100%,but the selectivity of N-benzyl aniline was low.After the reaction of aniline with benzyl chloride in the absence of solvent conditions,the by-product is separated in the reaction mixture and a single crystal is prepared.The X-ray single crystal diffraction test showed that the single crystal contained two kinds of crystals:C₂₀H₂₀NFeCl₄ and C₂₀H₂₀NCl?The composition and structure of the single crystal compound were determined by means of FT-IR,¹H-NMR,¹³C-NMR,XPS and elemental analysis.The benzylation reaction of aniline with?-Fe₂O₃ as catalyst in the medium of alkaline solvent to synthesize N-benzyl aniline,solves the problem of low selectivity of mono-substituted products.The experimental results show that the catalytic activity of catalyst?-Fe₂O₃ is very high.The reaction conditions were as follows:the reaction temperature was 60°C,the reaction time was60min,the reaction temperature was 60°C,the reaction time was 60 min,the reaction temperature was 60°C,the reaction time was 60 min,The amount of?-Fe₂O₃ was 0.1 g,the ratio of aniline and benzyl chloride was 3:1,the conversion of benzyl chloride was99.5%under the reaction conditions,and the selectivity of N-benzylaniline was 92.3%.