Study On The Related Factors Of Depression After Stroke

Objective: To investigate the related factors of depression after stroke in patients with acute stroke. Methods: 1 Patients with Hamilton Depression Scale for 96 cases of first stroke were divided into depression and non depression group. 2 Community Stroke Projec OCSP, Oxfordshire,, according to the Oxford County community stroke patients in ischemic stroke patients, analyze and study the incidence of various types of post stroke depression(depression post-stroke, PSD). 3 For all patients using the National Institutes of Health Stroke Scale(NIHSS score), Mo CA score to analyze the recovery of neurological function in stroke patients, and the correlation of the two groups were compared. And compared between the two groups of patients with basic information(including gender, age, culture degree, character, the recent negative events, family care, income, place of residence, type of stroke, general factors), brain stroke location, NIHSS score, OCSP type, homocysteine, hypersensitivity C protein and cognitive function were analyzed for comparison to determine the main factors affecting the occurrence of PSD. 4 The results of the use of SSPS17.0 to analyze the measurement and count data using T and chi square test method for testing, P<0.05 said the results were statistically significant difference. Results: 1. There were 96 patients in this study. The male and female were 55 and 41, respectively. The age range was 43-85 years. Cerebral hemorrhage and cerebral infarction were 11 and 85 cases, respectively. These patients were divided into depression group and non depression group by using the Hamilton depression scale, and the numbers were 34 and 62 respectively. Its occurrence rate is 35.4%. 2, Compared two groups of patients with basic information such as education level and The type of stroke have no statistically significant difference(P > 0.05); and gender,age,character, the recent negative events, family support, income and residence patients in the two groups have significant difference(P < 0.05). 3, Through the investigation of the history, the depression group and non depression group in terms of hypertension, diabetes exist significant difference(P < 0.01), and in the history of smoking and drinking history, no significant difference(P > 0.05). 4. The number of lesions in the left and right hemisphere The results showed that there was no difference in the incidence of PSD between the two groups(P>0.05). According to the Starkstein method, and the brain CT examination method was used to test that the lesions located in the front and back,the results showed that there was a difference in the incidence of PSD between the two groups(P<0.05). 5, According to the lesion occurred in the cortex, basal ganglia and the lateral ventricles, the cerebellum and other parts, and statistical comparison of the incidence of PSD in the two groups. The results showed that there was no statistical difference in the incidence of depression between the two groups(P>0.05). 6, In the OCSP classification: according to the statistical results showed that the probability of depression before the occurrence of depression in the first cycle of depression is higher, the results were statistically significant difference(p<0.05)..7,in the number of lesions and NIHSS score, Groups of patients were significantly different(p<0.05). 8, According to the statistical results showed that the depression group the homocysteine concentration was significantly higher than that of non depression group, and the two groups have significant difference(P < 0.01), and depression in the group of hypersensitivity C protein content is also significantly higher than those in non depression group, and two groups with significant differences(P < 0.05). 9, The Mo CA score of the depression group was significantly lower than that of the non depression group, and the two groups had very significant difference(p<0.01). Conclusion: 1 The incidence of PSD in the acute phase of stroke patients was 35.4%. 2 The occurrence of PSD is related to the location of cerebral injury, the character, family care, income and residence, and other general information. And in the number of lesions, NIHSS score, hypertension, diabetes, homocysteine, high sensitivity C reactive proteinare related risk factors of PSD.3 The probability of PSD in the patients with anterior circulation infarction was higher than that of the posterior circulation in the OCSP classification of ischemic stroke.4.PSD has a certain effect on cognitive function.