| Objectives: 1. Situation of Chinese medicine in chronic cholecystitis were reviewed and summarized clinical cases observed; 2. Modified Shuganlidan observed side effects in clinical treatment of chronic cholecystitis, and the mechanism of this side effect and research; 3. at the same time Chinese medicine is prevention and treatment of chronic cholecystitis lay the foundation for further development; 4. by Shuganlidan soup clinical studies of chronic cholecystitis, to lay the foundation for clinical medicine.Methods: According to the outpatient and inpatient wards(Wuhan City Chinese Medicine Hospital Gastroenterology in March 2012 to January 2016) the complete collection of clinical cases of 90 cases of patients with chronic cholecystitis; follow a random method in accordance with the guidance on the role of clinical trials, according to randomized The method is divided into two groups, the treatment group(plus or minus Shuganlidan party group) 45 cases were treated with decoction addition and subtraction Shuganlidan square oral control group(bile gold piece set) to 45 cases of bile medicine oral tablets gold treatment; more than two begin four weeks for a course of treatment after a detailed search of clinical symptoms by telephone, as well as review the hepatobiliary ultrasound before and after comparison, to observe whether the improvement compared two groups of treatment efficacy. Based plus features chamber, such as blood, stool examination, urine routine, liver and kidney function(blood test) with the hospital laboratory and clinical indicators and clinical symptoms of ECK and rays, symptom scores, abdominal symptoms, gallbladder imaging Evaluation of the efficacy of inspection indicators to show subtraction Shuganlidan side effect of chronic cholecystitis clinical effect, as well as Shuganlidan decoction in the treatment of chronic cholecystitis mechanism of action and discussion.Results: 1. This study enrolled 90 patients, including randomized controlled grouped into bile gold piece group(J group) 45, the severity score 12.02 ± 1.85 points; subtraction Shuganlidan party group(S) 45, severity score 11.85 ± 1.84 points; 2. the two groups no significant difference(p> 0.05) in the age distribution, but the data show that 40 to 59 year old age group suffer from the highest incidence of the disease; 3. treating symptom scores group, the control group was not given and when given to drug intervention showed that there were differences(P <0.05), and the administration of the drug after symptoms intervention subtraction Shuganlidan party group was significantly better than gold markedly gall-piece set; 4 plus Save Shuganlidan Party after a recovered drug intervention were 10, 15 effective, effective 18 people, 2 people, the total efficiency of up to 95.56%(to heal all treatment, effective treatment of patients with markedly accounted for the total group the percentage of cases); gold gall-piece set after cured by one after drug intervention, effective 20 people were cured, 14, invalid 10 people, the total efficiency of up to 77.78%(to heal all therapy, effective, effective cases accounted for gold there gall piece set percentage of all cases), plus or minus Shuganlidan side and gold sheet gallbladder patients by ?2 test analysis, statistical analysis showed a significant difference(P <0.05), and the addition and subtraction Shuganlidan party group efficiency significantly better than gold gall-piece set; 5. clinical treatment efficiency after analysis does not give drug intervention subtraction Shuganlidan side and gold gall sheet group there was no significant statistical difference(P> 0.05) before now both groups after drug treatment, in clinical cases showed signs and symptoms have a significant effect. Specific circumstances are as follows: Xie pain, abdominal tenderness, bowel show superior efficacy of S group J group(P <0.05); mouth and throat, nausea and vomiting can be seen clearly superior efficacy of group S Group J, with difference, There were statistically significant(P <0.01); anorexia eat less, lead shoulder pain, lassitude symptoms appear in the S and J group and no statistically significant efficacy difference(P> 0.05);. 6 drugs the treatment of the B-school video effect gallbladder showed that the treatment group, there were seven gallstones disappeared, reduced by 14 people, five were in no significant effect, the total effective rate was 73.08%; control group, no cases of disappearance of gallstones, 14 people of no therapeutic value, only seven stones were reduced, the total effective rate was 33.33%; 7 by ?2 test shows that a drug intervention group after gallbladder wall thickening aspect effective than the control group(P < 0.05); and for the gallbladder wall rough in the gallbladder ultrasound imaging and sound effects through the treated group was superior to the effect of visible S J group(P <0.01).Conclusion: 1. Oral Modified Shuganlidan can only significantly improve the clinical efficacy of chronic cholecystitis cases; 2 oral subtraction Shuganlidan in order to effectively improve chronic cholecystitis on ultrasound imaging performance; 3 oral subtraction Shuganlidan treating chronic cholecystitis treatment effect is significant, it is worth learning and reference in clinical practice. |
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