The Observation Of Using Botulinum Toxin Type A Combined Application Of Silicon Gel To Inhibit The Scar After Epicanthoplasty

Objective:Compare the study of botulinum toxin type A combined application of silicon gel with separateapplication of silicon gel,and observe the effect of epicanthoplasty postoperative scar.Methods:Collect the epicanthoplasty patients who used small incision dualeyelidoperation and the way“Y-V”at the same time of orthopedic sursery of the First Affiliated Hospital of Dalian Medical University from June 2014 to June 2015.Selected 40 patients as research subjects and divided into the observation group and control group randomly,each group of 20 patients.Observation group inject botulinum toxin type A at angulus oculinasalis immediately after taking out stitches 10 days(China Lanzhou scale botulinum toxin type A,100U/bottle),then inject 2U to the new point of angulus oculi nasalis.Inject 1U to the two each arms point and the depthof injection are strata subcutaneum,total dose of4 U.The patient of observation group and control group all use silicone gel after taking out stitches(American dermatix gel 15g/count)till 6 months after surgery,twice a day.Two groups of patients should return visit in 1 months’ and 6 months’ time after surgery.Adopt the international recommended OSAS scar evaluation,assessed and measured the angulus oculi nasalis by two rich-experienced doctors from the three aspects-scar color,smoothnessand scar width.0 point represent the color of the scar is light,and it is smooth and soft,that means the scar is close to normal skin and the scar is mature and stable.1 point represent the color of the scar is pink red,and it is a little convex or concave,that means the scar has a little differences and it is called mild hyperplasia.2 point represent the color of the scar is red,and it protrude the surface of the skin,that means the scar has obvious difference and it is called hyperplasia scar.The scar width should use verniercaliper(Accuracy 0.02mm)to measure.Unified select the right eye of each patient’s angulus oculi nasalis and the middle of the up and down eyelid scar.Assess the three fixed points corresponding incision scars,the value of each eye=the value sum of each point/3,scar width=the width sum of each point/3.Add the evaluation of the patients’ itching,0 point means painless itching,1 point means slightly itching,2 point means significantlyitching.Leave image data.The result adopt thestatistical software SPSS 17.0 to count and analysis.Results:1monthaftersurgery,scarcolor(t=6.52,P<0.01),smoothness(t=4.54,P<0.01),scar width(t=12.76,P<0.01)and itching(t=8.85,P<0.01)compared with the control group,and the difference has statistically significant(P<0.01);6 month after surgery,scarcolor(t=0.99,P=0.33),smoothness(t=1.05,P=0.30),anditching(t=1.24,P=0.22)compared with the control group,and the difference has no statistically significant(P>0.05);scar width(t=4.24,P<0.01),The two groups in different time all found scar color,smoothness,scar width and itching havestatistical difference between 1 month and 6 month after surgery(P<0.01).Conclusion:1、Compare the study of botulinum toxin type A combined application of silicon gel with separate application of silicon gel,the former can better inhibit scar hyperplasia after epicanthoplasty.2、Compare the study of botulinum toxin type A combined application of silicon gel with separate application of silicon gel,the former canreduce or eliminate the itching caused by scar hyperplasia and using silicone gel separately of postoperative recovery period.