| Objective: The purpose of this study was to assess the level of blood pressure control in patients with coronary heart disease (CHD) of China in order to provide guidance for the prevention and treatment of CHD.Methods: The patients with CHD were retrospectively collected from 2011 -2014 in PLA General Hospital and Hainan Branch Hospital. Then a retrospective clinical epidemiological analysis was made to investigate the current situation of blood pressure control in patients with CHD in China. Results: A total of 1230 patients were enrolled,including 758 males (61.63%) and 472 females (38.37%). Age range was 60-99 years old.(1) The blood pressure in percutaneous coronary intervention (PCI) group, coronary artery bypass grafting (C ABG) group and control group, male systolic blood pressure (SBP)were 135.66±19.03,125.73±17.44, and 134.93±16.48mmHg, female SBP were 140.20±16.43,138.6±6.98, and 134.88±16.18mmHg, male diastolic blood pressure (DBP)were 78.41±12.67, 69.77±9.61,and 78.56±11.43mmHg,and female DBP were 82.63±16.23, 74.3±9.14,and 78.25±11.51mmHg respectively. Male's SBP and DBP in CABG group were lower in PCI group and control group, and female's DBP in CABG group were lower in PCI group.(2) Usage rate of antihypertensive drugs: Usage rate of anti platelet drugs were 88.43%, ?-blockers 56.97%, angiotensin-converting enzyme inhibitor (ACEI) / angiotensin receptor antagonist (ARB) 64.55%, and statins 79.14%.(3) Compliance rate of blood pressure in smoking group and non smoking group were 45.67% and 55.18% (P=0.046), in drinking and non-drinking group were 49.32% and 54.48% (P>0.05), in exercise group and non-exercise were 53.77% and 53.55% (P>0.05).Conclusion: male's SBP, DBP and female's DBP after CABG were significantly lower than PCI. Smoking could significantly reduce the compliance rate of blood pressure. The usage of secondary prevention drugs of CHD in China was not satisfied. We needed to continue to strengthen the promotion of education to improve the usage rate of secondary prevention drugs.Objective: The purpose of this study was to assess the level of blood lipid in patients with coronary heart disease (CHD) of China in order to provide guidance for the prevention and treatment of CHD.Methods: The patients with CHD were retrospectively collected from 2011 -2014 in PLA General Hospital and Hainan Branch Hospital. Then a retrospective clinical epidemiological analysis was made to investigate the current situation of blood pressure control in patients with CHD in China. Results: A total of 1230 patients were enrolled,including 758 males (61.63%) and 472 females (38.37%). Age range was 60-99 years old.(1) Female's total cholesterol (TC),triglyceride (TG),low density lipoprotein (LDL) and high density lipoprotein (HDL) levels were significantly higher than male. There were significant difference in male's TG between CABG group and control group; there were significant differences in blood lipid compliance rate between PCI group, CABG group and control group, and patients in CABG group with the highest blood lipid compliance rate (18.75%). (2) Usage rate of CHD drugs: there were no significant difference on the usage rate of antiplatelet drugs, trimetazidine, nicorandil, hypotensors, hypoglycemic drugs and lipid-lowering drugs between dyslipidemia group and normal blood lipid group. While the usage rate of nitrates in dyslipidemia group were significantly higher than that in the normal blood lipid group. (3) Compliance rate of blood lipid in smoking group and non smoking group were 13.90% and 20.04% (P=0.049), in drinking and non-drinking group,the data were 17.02% and 19.60% (P>0.05), and in exercise group and non-exercise group,the outcome were 18.52% and 19.68% (P>0.05).Conclusion: The overall control of blood lipid in female was weaker than male. Male's TG level in CABG group was lower than control group and the compliance rate of blood lipid in CABG group were significantly higher than those in PCI group and control group,suggesting that CABG may improve the level of blood lipids in patients with CHD.Smoking could significantly reduce the compliance rate of blood lipid. We need further strengthen on the education and guidance to improve patient compliance, and carry out drug prevention as soon as possible in accordance with the guidelines.Objective: The purpose of this study was to assess the level of blood glucose control in patients of coronary heart disease (CHD) with diabetes mellitus (DM) in China in order to provide guidance for the prevention and treatment of CHD and DM.Methods: The patients with both CHD and DM were retrospectively collected from 2011-2014 in PLA General Hospital and Hainan Branch Hospital. Then a retrospective clinical epidemiological analysis was made to investigate the current situation of blood glucose control in patients of CHD with DM in China.Results: A total of 328 patients were enrolled, including 193 males (58.84%) and 135 females (41.16%). Age range was 60-99 years old (Average age 73.93). The overall blood glucose compliance rate was 49.7%. (1) Comparison of drugs used in CHD with different levels of blood glucose control: usage rate of aspirin, hypoglycemic drugs and lipid-lowering drugs in substandard blood glucose group were significantly lower than normal blood glucose group (80.6% vs 63.2%?97.05 vs 90.8%?95.2% vs 89.0%), while there were no significant differences among clopidogrel, nitrates, trimetazidine, nicorandil and hypotensor drugs between the two groups (p>0.05).(2) The usage of hypoglycemic drugs: The overall usage rate of insulin was 39%, the overall usage rate of oral hypoglycemic drugs were: metformin 41.8%, a glucosidase inhibitor 41.8%,sulfonylurea 29%, glinides 14.3%, thiazolidinediones (TZD) 4.6%. The usage rate of insulin in substandard blood glucose group was significantly higher than normal blood glucose group (p<0.05), while there were no significant differences in oral hypoglycemic drugs. (3) Lifestyle situation: smoking rate, drinking rate and exercise rate in normal blood glucose group were 14.1%, 14.1%, 49.7% respectively and 11.5%, 21.2%, 42.7% in substandard blood glucose group. There were no significant differences between two groups among lifestyles (p>0.05).Conclusion: The level of blood glucose control in patients with CHD combined with DM was still not ideal, which needed doctors and patients continue to make efforts. We should keep improving the way of life, carrying out the secondary prevention of hypoglycemic drugs as soon as possible, strengthen self-monitoring of blood glucose, correctly use the insulin and so on to make the blood glucose control in a reasonable range and reduce the incidence of diabetic complications and cardiovascular disease. |
PDF Full Text Request