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Evaluation Of Radix Scutellariae Ointment In The Treatment Of Post-operative Wound With Carbon Dioxide ?CO2? Laser In Hypertrophic Scar

Posted on:2018-07-23Degree:MasterType:Thesis
Country:ChinaCandidate:H G ShenFull Text:PDF
GTID:2334330515467813Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Objective:To evaluate the clinical efficacy and safety of scutellaria ointment in wound healing of proliferative scar lattice carbon dioxide?CO2?laser.Methods:30 patients with head hypertrophic scar were treated with CO2 lattice laser.All patients were from Jiangsu Provincial Hospital of Traditional Chinese Medicine,and were randomly divided into treatment group and control group.The patients were randomly divided into treatment group and control group.15 cases in each treatment group were treated with scutellaria ointment,and the control group was treated with chlortetracycline ointment.The pain index of the four time periods was observed after 30 minutes,24h,3 days and 7 days after operation.The histopathology of the granulation tissue was taken at 7 days after operation and at 7 days after operation.HE staining was performed and immunohistochemistry The expression of keratin 19?CK19?and transcription factor 63?P63?in the scars and normal skin of granulocytes,the wound healing time,the preoperative,postoperative month,the postoperative month The efficacy of latent laser combined with Scutellaria baicalensis ointment in the treatment of hypertrophic scar dot matrix carbon dioxide?CO2?laser treatment.The pain index was significantly lower in the treatment group than in the control group,and the pain relief time was significantly shortened,the difference between the two groups was statistically significant?P<0.05?,7d There was no significant pain in both groups,no statistically significant.2,histopathological observation:the treatment group and the control group of fiber bundles were homogeneous red dye,and arranged neat before treatment,fibrous cells less scar tissue less blood vessels.The expression of CK19 and P63 in the treatment group was higher than that on the 3rd day after treatment.The expression of CK19 and P63 in the treatment group was higher than that on the 3rd day after treatment.The expression of CK19 and P63 in the treatment group was higher than that in the control group Reached the peak,the first 7 days to reduce.The positive expression rate of CK19 and P63?80%,73.33%?in the treatment group was significantly higher than that in the control group?33.33%,26.67%?,the difference was statistically significant?P<0.05?.?8.23 ± 2.78?d in the treatment group was significantly better than that in the control group?10.55±2.98?days,the difference was statistically significant?P<0.05?.There was no significant difference between the two groups?P>0.05?.There was no significant difference between the two groups?P>0.05?.There was no significant difference between the two groups?P>0.05?.The total effective rate was 86.67%in the treatment group was significantly higher than that in the control group?46.67%?,there was significant difference?P<0.05?.The incidence of 6.67%in the treatment group was significantly lower than that in the control group?46.67%?,and there was significant difference?P<0.05?.Conclusion:The treatment of hypertrophic scar dot matrix carbon dioxide?CO2?laser treatment,using scutellaria ointment care,not only can promote wound repair,accelerate healing,but also can reduce the pain after laser treatment,but also improve the appearance,reduce pigmentation,The effect is obvious,worthy of promotion.
Keywords/Search Tags:lattice carbon dioxide laser, scutellaria ointment, hypertrophic scar, wound healing repair
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