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Clinical Research Of Xuefu Zhuyu Capsule In Treating Senile Chronic Subdural Hematoma

Posted on:2018-01-25Degree:MasterType:Thesis
Country:ChinaCandidate:W TianFull Text:PDF
GTID:2334330515962315Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
As China is about to enter an aging society,geriatric diseases are getting more and more attention.Chronic subdural hematoma(CSDH)is a most common type of older intracranial hematoma,This disease is easily misdiagnosed,missed and then delayed due to the onset of more hidden,and has a poor prognosis overall.Chronic subdural drainage is one of the commonly used methods for surgical treatment of CSDH currently.Although its cure rate has been significantly improved in our country,due to the improving of medical level and the great progress of diagnostic technology,CSDH is still difficult to treat clinical,because of the poor surgical tolerance and physique of elderly patients and some other reasons,and residual hematoma,postoperative infection,slow recovery after surgery and hematoma recurrence are common phenomena.Therefore,with oral Xuefuzhuyu capsule for adjuvant therapy in the perioperative period,elderly patients can receive a better effect.Objective: Provide a systematic and scientific basis for the treatment of CSDH combined with traditional Chinese and western medicine by observing the clinical effect of combined traditional Chinese medicine Xuefuzhuyu capsule in the treatment of chronic subdural hematoma in elderly patients.Methods: Data were collected from patients with neurosurgical chronic subdural hematoma in our hospital,from June 2015 to June 2016,a total of 50 patients.The subjects with the inclusion criteria were divided into experimental group and control group using random grouping method,which there were no significant differences in gender,age,bleeding volume,bleeding site and Glasgow coma score(GCS).Patients with allergies or allergies to a variety of drugs,high blood pressure,diabetes,coagulation dysfunction,liver,kidney,and other serious primary disease were excluded,and the two groups are comparable.The patients in control group were treated by traditional drilling and drainage,while the experimental group increased Xuefuzhuyu capsule for adjuvant therapy on the basis of the control group.Compare the indicators in: 1.Clinical symptoms 2.Hardening hematoma volume of the value(imaging examination)3.Average hospital days 4.Glasgow coma score of the two groups and quantify them.The clinical observation values of all patients were input to the computer and analyzed by t test using SPSS 17.0 software.Results:1.The experimental group: 27 cases,9 females,18 males,from 50 to 79 years old,mean age 60.89 ± 3.122 years.The control group: 23 cases,8 females,15 males,from 51 to 80 years old,mean age 59.72 ± 3.341 years.Age(P = 0.1259),age comparison results(P> 0.05),indicating that the two groups are comparable.2.Two groups of patients were diagnosed by head CT.The experimental group: 23 cases of unilateral hematoma,4 cases of bilateral hematoma,among them there were 16 cases of right frontal lobe,4 cases of bilateral frontal,5 cases of right frontal and 5 cases of right occipital according to the different parts of the bleeding section,hematoma volume was from 31 to 133 ml,an average of 72.56 ± 5.204 m1.The control group: 21 cases of unilateral hematoma,2 cases of bilateral hematoma,among them there were 13 cases of left frontal lobe,2 cases of bilateral frontal and 8 cases of right side of the frontal temporal according to the different parts of the bleeding section,hematoma volume was from 42 to 131 ml,an average of 70.61 ± 4.743 m1.Bleeding volume and section(P = 0.7863),the difference was not statistically significant(P> 0.05),indicating that the two groups were comparable.3.The average GCS score was 13.38 ± 0.3035 points in the experimental group,and 23.39 ± 0.4859 points in the control group.According to statistical analysis,GCS scores of the two groups had significant differences(P = 0.0081<0.05).4.The reduction of the average postoperative hematoma was 63.30 ± 5.300 ml in the experimental group,and 58.52 ± 5.043 ml in the control group.According to statistical analysis,hematoma reductions of the two groups had no significant differences(P = 0.6120>0.05).5.The average hospitalization time was 10.07 ± 0.3373 days in the experimental group,and 13.39 ± 0.6526 days in the control group.According to statistical analysis,hospitalization time of the two groups had significant differences(P = 0.0019<0.05).6.The cure rate was 92.59% in the experimental group,and 92.59% in the control group.The cure rate of the experimental group was higher than that of the control group.Conclusion:1.Xuefuzhuyu capsule can improve the GCS score of chronic subdural hematoma after surgery in the elderly.2.Xuefuzhuyu capsule can improve the cure rate of chronic subdural hematoma in the elderly.3.Xuefuzhuyu capsule can significantly shorten the hospitalization time of elderly patients with chronic subdural hematoma.Xuefuzhuyu capsule can shorten the Hospitalization time,reduce the incidence of complications,effectively shorten the drainage tube retention time,enhance the elderly patients for surgical tolerance,reduce the risk of recurrence,improve the quality of life of patients in the adjuvant treatment of elderly chronic membrane hematoma process.
Keywords/Search Tags:chronic subdural hematoma, Xuefu Zhuyu capsule, drilling drainage, subdural hematoma
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