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Study On The Prevalence Of Metabolic Syndrome And Its Influencing Factors In Community Medical Check-up Crowd

Posted on:2018-03-10Degree:MasterType:Thesis
Country:ChinaCandidate:H Z SunFull Text:PDF
GTID:2334330518454504Subject:Epidemiology and medical statistics
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Objective : To understand the prevalence of metabolic syndrome(MS)and its influencing factors in community medical check-up crowd to provide scientific basis for prevention and control of MS.Methods:Residents aged 18 and older who took medical check-up in a community were selected by cluster sampling.Data related MS and its influencing factors were obtained by questionnaires,physical examination and laboratory tests.Non-conditional logistic regression model was used to analyze the related influencing factors of MS.Results:1.A total of 610 participants were eligible for the study,including 334 males(54.8%)and 276 females(45.2%).According to the diagnostic criteria of CDS,The crude prevalence of MS was 13.4%(82/610),and there was no significant difference between male and female(15.6% and 10.9%,respectively).2.The subjects who were older had the lower degree of culture,or a family history of hypertension or diabetes mellitus,and failure to exercise or excessive salt intake had a higher MS prevalence compared to the controls.The prevalence of MS increases with age.The prevalence of different ages in 18 to 44,45 to 59,and above 60 years old were 7.5%(19/252),7.5%(33/200)and 19.0%(30/158),respectively;The prevalence of MS in different education levels were 19.4%(28/144)in primary school and below,13.3%(26/195)in middle school and 10.3%(28/271)in college degree and above,respectively;The prevalence of MS in subjects who ate excessive salt intake or not were 11.5%(54/469)and 19.9%(28/141).The prevalence of MS were17.2%(55/319)and 9.3%(27/291)in subjects who exercised more than two times a week or not.The prevalence of MS were 9.8%(49/499)and 29.7%(33/111)who had a family history of hypertension or not.The prevalence of MS were 11.2%(61/545)and 32.3%(21/65)in subjects who had a family history of diabetes or not.The comparisons of different MS prevalence were statistically significant.The distributions of occupation,income,smoking or not,and excessive red meat intake or not were found no significant difference in MS patients and controls.3.In accordance with the mumerical value,the prevalence of MS components were30.3%(185/610)in obesity,25.4 %(155/610)in high TG,22.6%(138/610)in hypertension,16.6%(101/610)in hyperglycemia,and 8.7% in low HDL-C,respectively.The most common combination were obesity,hypertension and dyslipidemia(34.1%).In addition to low HDL-C,the detection of MS women more than men,obesity,high TG hematic disease,high blood pressure,high blood glucose detection rate were men than women.4.Except that the level of HDL-C in MS patients was lower than the controls,the level of BMI,WC and other physical examination and laboratory examination indexes in patients were higher than the controls.5.The level of RDW-CV in MS patients was significantly higher than that in the control group(P < 0.05).Among the components of MS,the level of RDW-CV in hyperglycemia group and low HDL-C group were higher than that in the control group with statistical difference.However,the distribution of RDW-CV in other components were not obvious different in the case and control groups.6.Multivariate Logistics regression analysis showed that older age,family history of diabetes,longer waist circumstance,bigger body mass index,hypertension,higher triglyceride and lower high density lipoprotein cholesterol were risk factors for MS.The odds ratio and its 95% confidence interval were 1.049(1.003-1.098)for older age,0.356(0.132-0.784)for family history of diabetes,1.241(1.088,1.426)for longer waist circumstance,1.048(1.001,1.097)for bigger body mass index,1.040(1.017,1.063)for hypertension,2.504(1.881,3.335)for higher triglyceride,and 0.323(0.138,0.755)for high density lipoprotein cholesterol,respectively.Conclusions:Given that quite proportion of community adult residents had MS,targeted prevention and control measures for the risk factors should be taken early.It is of great significance to improve self health management consciousness,strengthen the movement,prevent overweight and obesity,take a rational diet(reducing salt and red meat intake),control the occurrence and development of MS and reduce the morbidity and mortality of cardiovascular diseases risk.Objective: Metabolic syndrome(MS)increases the risk of type 2 diabetes mellitus(DM)and other chronic diseases.A comprehensive understanding prevalent status of MS is necessary for controlling it.But the prevalence of Mt S reported in studies varied widely in different Chinese populations.The aim of this study was to systematically estimate an overall prevalence of MS in China.Methods: The electronic databases were searched for relevant studies published from January,2011 to December,2015.Meta analysis was used to estimate the pooled prevalence of MS according to different diagnostic criteria.Subgroup and sensitivity analysis were also conducted.Results: In total,37 articles were performed in this meta-analysis,including 23country-or city-based studies and 14 province-based studies.The pooled prevalence of MS was 30.6%(23.6-37.7)for NCEP-ATPIII,27.5%(23.4-31.6)for IDF and36.5%(29.0-44.1)for JIS in country-or city-based studies and 24.9%(22.0-27.8)for NCEP-ATPIII,22.7%(13.5-31.9)for IDF and 24.4%(20.5-28.8)for JIS in province-based studies.Subgroup analysis showed the prevalence of MS in women was higher than that in men based on the three criteria.The prevalence of MS in urban residents was higher than that in rural according to NCEP-ATPIII and IDF.However,the reverse result was obtained based on JIS.Sensitivity analysis showed that the pooled prevalence was stable as a whole.Conclusions: This meta-analysis demonstrated increasing prevalence of MS in Chinese adults regardless of the different criterion.Effective public health strategies for preventing MS should be developed to reduce medical burden in China.
Keywords/Search Tags:Metabolic syndrome, Prevalence, Epidemiological investigation, metabolic syndrome, prevalence, meta-analysis, China
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