Pleural Adhesion Of Tuberculous Pleural Effusion And Analysis Of Related Factors

Objective:This study aim to explore the possible factors affecting the degree of pleural adhesion by grading the severity of pleural adhesion using medical thoracoscopy.Methods:A total of 70 patients with tuberculous pleural effusion diagnosed by local anesthesia-assisted thoracoscopy were selected from the respiratory department of the first affiliated hospital of Kunming Medical University from January 2015 to January 2017 and the severity of pleural adhesion was divided into 6 levels.Related variables including pH,adenosine deaminase,lactate dehydrogenase,total protein,red blood cell count,white blood cell count,percentage of mononuclear cells,glucose,chloridion,peripheral blood white blood cell count,C-reactive protein,age and duration were analyzed for the relationship with the severity of pleural adhesion.All of the data above were analyzed using SPSS17.0 software package.Measurement data with normal distribution were shown with mean +/-standard deviation,nor the interquartile range(P25,P50,P75).The count data were shown with the number of cases or rate.Correlation factors analysis associated with the severity of pleural adhesion were carried out using the Kruskal-Wallis H test,Spearman rank correlation analysis and orderly multiple Logistic regression analysis.Target variables were those with the significant probability of F and P<0.05 means the difference is statistically significant.Results:.In pleural effusion adenosine deaminase,lactate dehydrogenase,total protein,percentage of red blood cells,white blood cells,monocytes,glucose,chloride ion,peripheral blood leukocyte,c-reactive protein and neural specificity enolization enzyme,glucose,and patients age factors such as p values were greater than 0.05,there were no statistical significance.The severity of pleural adhesion pleural adhesion in 70 patients was divided into grade 0(n=11),grade 1(n=25),grade 2(n=16),grade 3(n=10),grade 4(n=8),grade 5(n=0),respectively.The correlation coefficient of PH is 0.874,p<0.01,the results are statistically related.The correlation coefficient of duration is 0.954,p<0.01,the results are statistically related.The severity of pleural adhesion was not significantly related with adenosine deaminase,lactate dehydrogenase,total protein,red blood cell count,white blood cell count,percentage of mononuclear cells,glucose,chloridion,peripheral blood white bl ood cell count,C-reactive protein,and age(p>0.05).Conclusions:The pleural adhesion of tuberculous pleural effusion could be classified by medical thoracoscopy.PH in pleural effusion was the protective factor,and the duration of disease was the risk factor for the increase in the degree of pleural adhesion.Therefore,pH and duration are helpful to the prediction of the severity of pleural adhesion.Toadenosine deaminase,lactate dehydrogenase,total protein,red blood cell count,white blood cell count,percentage of mononuclear cells,glucose,chloridion,peripheral blood white blood cell count,C-reactive protein,and age are not related with the prediction of the degree of pleural adhesion.