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The study of correlation between cervical intervertebral disc degeneration and Miyazaki grading systemObjective:To analyze the relationship between the cervical intervertebral disc segments,sex and age of subjects and Miyazaki grading,to investigate the physiological factors related with the degeneration of cervical intervertebral disc,lay the foundation for the subsequent quantitative analysis.Materials and Methods:From June to October in 2016,82 patients with cervical MRI were examined.Using GE Signa HDXT 1.5 T superconducting MRI,CTL spine phased array coil for cervical spine scanning.Conventional sagittal T2WI images were collected by FSE sequence.The cervical intervertebral disc was graded according to the Miyazaki classification criteria.Apply SPSS 22.0 software.The Miyazaki grading of the cervical intervertebral disc was analyzed statistically with the cervical disc segment,the sex and age of the subjects.Results:In the study a total of 410 cervical intervertebral disc segment,18 Miyazaki grade I,94 grade II,204 grade III,83 grade IV,11 grade V.There were significant differences in Miyazaki level between different cervical intervertebral disc segments(P=0.003).There was no significant difference in Miyazaki level between the cervical intervertebral discs of different genders(P=0.172).In addition,except for grade IV and V,there was significant difference in the age of Miyazaki in different cervical intervertebral discs.There was a positive correlation between age and cervical Miyazaki grade(r=0.554,P=0.000).Conclusion:Miyazaki grading system as a dedicated evaluation of cervical disc degeneration of the imaging grading system for the assessment of cervical disc degeneration has a certain value.But it is based on the signal strength of the subjective visual assessment system,and can not be early detection and quantification of degeneration of the disc.Part ? The study of correlation between cervical intervertebral disc degeneration and T2 Mapping imagingObjective:1.5T magnetic resonance T2 Mapping quantitative imaging technique was used to measure and compare the cervical intervertebral disc with Miyazaki standard.So as to evaluate the diagnostic value of T2 Mapping quantitative imaging technique for the diagnosis of cervical intervertebral disc degeneration and provide the basis for the quantitative diagnosis of cervical disc degeneration by imaging method and provide a reference for clinical quantitative diagnosis of intervertebral disc degeneration.Materials and Methods:From June to October in 2016,a total of 81 patients with clinically diagnosed or suspected cervical spondylosis were enrolled in the MRI examination.Check time was 7:30-9:00 in the morning.The cervical spine was scanned with GE Signa HDXT 1.5T superconducting MRI,using a CTL spine phased array coil.The scan sequences included sagittal T2WI?T1WI and T2 pressure lipid,transverse T2WI and sagittal T2 mapping.Grading of cervical disc degeneration was done based on the T2WI median sagittal image and the Miyazaki grading standards The T2 mapping original data was transferred to the GE AW 4.6 post-processing workstation,using the Functool/T2 mapping software,set the T2 value range of the color scale on the pseudo color map.After the data was reconstructed and analyzed by software,the T2 relaxation time pseudo-color map was obtained.Finally,selected the T2 relaxation time original data map corresponding to T2 relaxation time pseudo color median sagittal as the level of interest.Combined with pseudo-color display,C2?C7 intervertebral disc nucleus pulposus area from front to back was divided into 5 equal parts,selected 5 regions of interest(ROls).The size of ROI was about 5mm2.T2 relaxation values of each region of interest were measured 3 times,and finally take the average.The T2 value of the nucleus pulposus was derived from the average of the T2 values of the five regions of interest.Apply SPSS 22.0 software.Analyze the relationship between the T2 value of cervical intervertebral disc nucleus and different Miyazak grades,different regions of Miyazaki grade,different segments,different regions of the same segment,and the gender and age group(?35,>35 to 50,>50)of the subjects.Results:81 subjects with a total of 405 cervical disc,15 Miyazaki grade ?,91 grade ?,216 grade ?,75 grade IV,8 grade V.A total of 397 cervical discs were included in the study.There was a significant difference in the T2 value of cervical intervertebral discs with different Miyazaki grading(F=10.150,P=0.000).And Dnnett T3 test,the differences between the grades were also statistically significant.The T2 value was negatively correlated with Miyazaki grading(rs=-0.833,P=0.000).There was a significant difference in the T2 value of cervical intervertebral disc nucleus pulposus in different areas of the same Miyazaki grade(P=0.000).There was a significant difference in T2 value of cervical intervertebral disc nucleus pulposus between different segments of cervical intervertebral disc(P=0.000).And the T2 value was weakly positive correlation with the segment(rs=0.363,P=0.000).There was a significant difference in the T2 value of cervical intervertebral disc nucleus pulposus between the same segment and different region(P=0.000).Each segment of cervical intervertebral disc,there were no significant differences between genders and nucleus pulposus T2 values.There was a significant difference between age group and cervical intervertebral disc nucleus pulposus T2 values(P = 0.000).Dnnett T3 test,the differences between the groups were also statistically significant.The age and the T2 value were moderately negative correlation(rs=-0.550,P=0.000).Conclusion:T2 mapping can quantitatively evaluate the early degeneration of the cervical intervertebral disc.It is possible to evaluate the physiological state and degeneration degree of living intervertebral disc objectively and noninvasively,providing the basis for early diagnosis and early prevention and treatment of cervical intervertebral disc degeneration. |
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