The Clinical Curative Effect Analysis Of Thrombolysis And Anticoagulation In Intermediate-risk Acute Pulmonary Embolism

Objective:To investigate the application and clinical efficiency of thrombolysis and anticoagulation in treatment for intermediate-risk APTE.Methods:Choose patients with intermediate-risk APTE from the center of Vascular Surgery in No.4 hospital of Kunming Medical University between Jan.2016 and Dec.2016.Inform patients simply anticoagulation and thrombolysis combined anticoagulation two plans,let patients choose and sign consent to treatment.Among 66 patients,31 cases treated by simply anticoagulation represent Group A(control group),while 35 cases treated by thrombolysis combined anticoagulation represent Group B(treatment group).To estimate the effect of treatment,a series of objective indexes were compared between the 2 groups,including clinical symptoms and the results of cardiac uhrasonography,spiral CT pulmonary angiography(SCT-PA)before and after treatment.Results:1.The clinical symptoms were improved in both groups after treatment.The clinical indicators such as pulmonary embolism areas,PASP,PaO2 and SaO2 changed significantly after treatment in the two groups(p<0.05).2.The effective rates of two groups were respectively 77.42%(A)and 97.15%(B).There was statistically significant difference between the two groups(p<0.05).3.There was a total of 6 cases with bleeding events in Group A;In Group B,there was a total of 8 cases.The bleeding rate of Group A was 19.35%,while the bleeding rate of Group B was 22.86%.There was no statistically significant difference in bleeding rates between the two groups(p>0.05).Conclusion:1.For patients with intermediate-risk APTE,no matter use thrombolysis combin-ed anticoagulation therapy or simply anticoagulation therapy,The patient’s clinical symptoms were improved.2.Using thrombolysis combined anticoagulation therapy can obtain clinical effect better and do not increase the risk of bleeding.