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Individualized Treatment Of Basal Ganglia Region The Prognosis Of Hypertensive Cerebral Hemorrhage Short-term Clinical Research

Posted on:2018-07-18Degree:MasterType:Thesis
Country:ChinaCandidate:X L GongFull Text:PDF
GTID:2334330533464665Subject:Clinical medicine
Abstract/Summary:PDF Full Text Request
Objective: Investigate the clinical efficacy of basal ganglia region hypertension cerebral hemorrhage treatment,analyze the related factors affecting the short-term prognosis,in order to improve the cure rate and reduce morbidity in patients.Methods: This study in combination with related literature and abroad on the basis of the results of the study and clinical experience,retrospective analysis of xinjiang uygur autonomous region people’s hospital neurosurgery in May,2013-December 2016 176 cases of cerebral hemorrhage patients inclusion and exclusion criteria.The clinical data of the following variables selected for the factors affecting the prognosis:the personal data(age,gender),past medical history(including the history of high blood pressure),preoperative general situation(including preoperative systolic blood pressure,preoperative blood sugar levels,preoperative GCS score)and preoperative CT performance(including bleeding,hematoma volume,whether hematoma shape,intraventricular hemorrhage,midline shift),operation time,operation method,complications(including postoperative bleeding,lung infection,upper gastrointestinal bleeding);Choose Activity of daily living(ADL)score as neural functional recovery after 1 month of standard,according to the clinical prognosis is divided into two groups: group 1,prognosis is good,the ADL score of level I,II,III;2,the poor prognosis group,the ADL scale of grade IV and V.Chi-square test is used in univariate analysis to analyze whether each influencing factor is statistically significant.;Then statistically significant factors are inducted into multiple logistic regression models to analyze This study combines with the previous literature and clinical experience.Results:(1)This study collected 176 patients required for research.117 cases among them male,59 cases female,aged 30 ~ 80,the average(54.47 + 9.23)years old,and past history of hypertension between 1 ~ 31 years,average(6.95-5.76)years,preoperative systolic blood pressure values between 128 ~ 224 mmHg,average(147.76 + 27.51)mmHg,preoperative blood glucose values between 4.2 ~ 22.2mmol/L,the average(8.02 + 3.53)mmol/L,preoperative GCS score between 6 ~ 14 points,the average(10.65-2.32)points,the left basal ganglia region 95 cases,81 cases of right basal ganglia,hematoma volume between 24~ 65 ml,the average(38.42 + 10.22)for ml,irregular hematoma form 77 cases,bleeding from the broken into the ventricle hemorrhage in 41 cases,midline shift in 45 cases,operation time between 8 ~ 72 h,the average(21.46 + 8.35)h,95 cases of minimally invasive hematoma puncture,81 cases of craniotomy,16 cases of postoperative secondary bleeding,pulmonary infection in 63 cases,9 cases of upper gastrointestinal bleeding,good prognosis of 86 cases,90 cases of poor prognosis.(2)the single factor analysis using Chi-square test: age,preoperative patients with systolic blood pressure,preoperative blood sugar levels,preoperative GCS score,hematoma volume,hematoma form,operation time,intraventricular hemorrhage,midline shift,postoperative bleeding,lung infection.(3)Multivariate analysis the statistically significant factors with Logistic regression model,0.05 for the test level.show that the independent risk factor including patients’ age,preoperative blood glucose value,preoperative GCS score,hematoma volume,operation time and prognosis has negative correlation;Whether hematoma rules,whether intraventricular hemorrhage,lung infection of postoperative hemorrhage was a positive correlation with prognosis.Conclusions: Basal ganglia region were retrospectively analyzed in patients with hypertensioncerebralhemorrhage early prognostic factors,and get the following conclusion:1.The single factor analysis using Chi-square test instructions to patients’ age,preoperative bloodglucose value,preoperative GCS score,hematoma volume,hematoma shape,operation time,intraventricular hemorrhage,midline shift,postoperative bleeding,lung infection again 10 factorshave an effect on the prognosis of patients.2.Multivariate logistic regression model analysis shows that the patient age,preoperative bloodsugar levels,preoperative GCS score,hematoma volume,whether intraventricular hemorrhage,surgical procedure,postoperative bleeding or not,whether the lung infection is the key influencing factors.Clear related factors in clinical attention and intervention and treatment,the recovery of neural function in patients with a positive effect,achieve the purpose of improving the prognosis of patients,to improve the cure rate and reduce morbidity of patients have clinical significance.
Keywords/Search Tags:Basal ganglia region, Hypertensive intracerebral hemorrhage HICH, affecting factors, prognosis
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