Clinical Effect Of Retaining Stent Combined With Chitosan In Tubal Anastomosis

Objective:To explore the clinical effects of retaining stents combined with chitonsan for fallopian tube operations in open vision.Methods: There were 119 cases fallopian tube operation which received treatment in the department of Gynecology of the First affiliated Hospital in Lanzhou University and Jiuquan people’s Hospital between January 2010 and December 2015,which divided into three groups according to operation methods which were 44 cases anastomosis of tube without stents(A group),39 cases anastomosis of tube retaining stents(B group)and 36 cases anastomosis of tube with stents and the chitonsan(C group).All patients were treated with uterine tube anastomosis,postoperative fluid management and followed-up visit.Among the three groups,statistic and analyze the differences in the rates of fallopian tube recanalization,intrauterine pregnancy,the ectopic pregnancy and the pregnancy in different period after fallopian tube operations as well as the obstruction rate at one year after operations.And the effects on renewal pregnancy of operation methods in controlling birth,ligation site,postoperative tubal length and patients ’ age also need to be analyzed.Results:1.The tubal recanalization rate in group C was significantly higher than that in group A and B,the difference was statistically significant(P<0.05),there was no statistical difference between the group B and the group A(P>0.05).2.The intrauterine pregnancy rate in group C was significantly higher than that in group A and B,the difference was statistically significant(P<0.05),the intrauterine pregnancy rate between the group B and the group A and the ectopic pregnancy rate among three groups had no statistical difference(P>0.05).3.The pregnancy rate at 4-8 months after operations in group C was higher than that in group A and B,the difference was statistically significant(P<0.05),the pregnancy rate at 4-8months after operations between the group B and the group A and at 9-13 months and 14-18 months among three groups had no statistical difference(P>0.05),the pregnancy rate decreased with time prolonged in all groups.4.The recurrent obstruction rate at one year after operation in group C was significantlyhigher than that in group A and B,the difference was statistically significant(p<0.05)5.The renewal pregnancy rate after operation among silver embolization method,cor e-cutting method and the double fold ligation method had no statistical difference(P>0.05).6.The renewal pregnancy rate in the isthmus operation was higher than that in the gorge-ampulla and the ampulla,the difference was statistically significant(P<0.05),there was no significant difference between the gorge-ampulla and ampulla(P>0.05).7.The renewal pregnancy rates in bilateral uterine tube length more than 5cm,unilateral more than 5cm,bilateral less than 5cm after uterine tube anastomosis were respectively76.17%,56.41%,5.88%,the difference was statistically significant between any two groups among the three groups(P<0.05).8.There was no statistical difference of the renewal pregnancy rate among the age of25-29,30-34 and 35-40 after uterine tube anastomosis(P>0.05).Conclusion:1.Retaining stents combined with chitosan after uterine tube anastomosis could increase the tubal recanalization rate and intrauterine pregnancy rate.2.After tubal anastomosis,the pregnancy rate decreased with the prolongation of time.