Epidemiological Characteristics Analysis Of Syphilis In Wuxi City From 2006 To 2015

Objective To understand the epidemic characteristics and influencing factors of syphilis in Wuxi in 2006-2015,and explore the countermeasures and provide theoretical basis for scientific prevention and control of syphilis.Subjects and Methods We collated and analyzed the syphilis case reporting in Wuxi from 2006 to 2015,Excel2007 and SPSS20.0 for statistical analysis were used,including reporting incidence,constituent ratio,average annual growth rate or decrease rate and trend chi square test,etc.The significance level of all statistical tests was defined as P < 0.05.Results1.During 2006-2015,23212 cases of syphilis were reported,the average annual incidence of syphilis was 49.55 per 100 000 person-year.The reported syphilis incidence were increased from 29.79 per 100 000 person-year to 68.06 per 100000 person-year in 2006-2009,and then decreased from 68.06 per 100 000 person-year to 44.20 per 100 000 person-year between 2009-2015.2.The incidence rate of primary syphilis,secondary syphilis,tertiary syphilis,latent syphilis and congenital syphilis were 13.79,17.74,0.18,16.79 and 1.05 per 100 000 person-year,respectively.The reported incidence rate of primary syphilis,secondary syphilis and latent syphilis was higher than others.The variation trend of reported incidence rate in syphilis among different stages were different in the decade.The annual incidence of primary syphilis,secondary syphilis and congenital syphilis firstly increased and then decreased.The average annual growth rate of reported latent syphilis was 16.72%,increased year by year during 2006-2015(P< 0.001).3.Syphilis were all reported in every district of Wuxi.The top three incidence areas were Chongan District(76.26 per 100 000 person-year),Beitang District(58.98 per 100 000 person-year),Xishan District(8.98 per 100 000 person-year).The incidence of the urban areas was distinctly higher than the rural areas.And the difference was statistically significant(P<0.001).4.The total reported incidence rate of syphilis in male and female during 2006-2015 was 50.39 and 48.73 per 100 000 person-year,respectively.The morbidity of male was higher than that of female and the difference was statistically significant(P<0.05).The incidence of primary syphilis and congenital syphilis of men was higher than that of women(P<0.05);the incidence of latent syphilis in female was higher than that of male(P<0.05);there was no statistical differences between the incidence of male and female in secondary syphilis and tertiary syphilis.5.The majority reported syphilis incidence was among 15-64 age groups,accounting for 89.33% of the total report.The constituent ratios of reported number among 55-64 and >64 age groups increased year by year,which increased from 7.84% and 5.35% in 2006 to13.22% and 17.22% in 2015,respectively.The constituent ratios of the patients over 55 years of age in the past ten years was rising(P<0.001).6.Among the reported cases in 2006-2015,the number of farmers was the highest,5525 cases(23.80%),followed by 5076 cases of housework and unemployment(21.87%),and 3362 workers(14.48%).The number of the cases with level of education below junior middle school was more than that with level of education above junior middle school.7.The influences of seasonal factor on the number of reported syphilis cases system was analyzed in numerical method.The seasonal cycle of syphilis was one year.In each season syphilis could be reported.The cases were less in January,February,April,October,November,December while the cases were more in March,May,June,July,August,September.The seasonal characteristic was obvious,every year around February hit the lowest point and then began to rise,rising in March there was a slight fluctuation,the first peak was reached in 6-8 months,subsequently,the number of cases began to decline to the low point.ConclusionsThe incidence of syphilis reported in Wuxi was a trend that rised first and then declined.And the rate of male was higher than that of female,and the incidence in urban areas was higher than that in rural areas.The number of cases reported increased year by year in the elderly.The focus groups of syphilis prevention in Wuxi were young and migrant workers,AIDS high-risk groups were also syphilis prevention focus groups.Strengthening the screening of syphilis in the medical institutions is an important means of prevention and control of syphilis.It is also necessary to strengthen maternal syphilis screening,and do a good job of blocking maternal and infants and reduce the fetal syphilis cases effectively.