The Evaluation Of Gd-DTPA At Low Concentration As An Oral Positive MRI Contrast Agents For The Duodenal Diverticulum

Objective:To investigate the feasibility of using the gadolinium-DTPA(Gd-DTPA injection)at low concentration as a positive MRI contrast agents to diagnose the duodenal diverticulum.Methods:From September 2013 to December 2016,MR images were retrospectively performed in 66 patients with duodenal diverticulum conformed by gastroscopy or Endoscopic Retrograde Cholangio—Pancreatography(ERCP)or in Taizhou People's Hospital.Retrospect of the MRI material of these 66 patients,compare their oral contrast agent and without oral contrast agent scan result with the gold standard including gastroscopy and ERCP.By using statistical analysis,and we can get the difference of two MRI scan accuracy and difference.Results:Among 95 patients,66 patients performed by gastroscopy,and 70 duodenal diverticulums found.While 29 patients performed by ERCP and final 35 duodenal diverticulums were found.So totally 105 duodenal diverticulums were found.Using gastroscopy or ERCP result as gold standard,MRI thin layer scan without oral contrast can find 90 duodenal diverticulums,missing 15.While MRI thin layer scan with oral contrast can find 103,only missing 2.By using statistical analysis we can get the accuracy and sensitivity is 85.71%(90/105)?98.1%(103/105)respectively,while the misdiagnosis was 14.29%(15/105)?1.9%(2/105).So,oral contrast agent MRI scan has significant advantage.Conclusion:MRI thin layer scan with oral low concentration of contrast agent can help to the diagnosis of duodenal diverticulum,which show better result than normal MRI thin layer scan.Three-dimensional reconstruction was comparable with upper gastrointestinal barium meal examination.It can be used as a powerful supplement for the suspicious diverticulum diagnosis.