Clinical Observation Of Senile Insomnia Treated Of Blood Deficiency Sputum Disturbance Type By Modified AnHun Decoction

OBJECTIVE: To observe the clinical efficacy of Modified AnHun Decoction in treatment of old-aged insomnia with blood deficiency disturbance and its influence on patients’ quality of life,summarize clinical experience,and enrich clinical evidence.METHODS: One hundred and eighty eligible elderly patients with insomnia with blood deficiency disturbance were selected and divided into 60 groups with randomized control principles.There were three groups in total.The traditional Chinese medicine group was Modified AnHun Decoction orally;Western medicine group: Ezilazole tablets were taken orally;Combined group: Modified AnHun Decoction + Estazolam Tablets for Oral Administration,using the “PSQI Sleep Quality Index Scale”,self-designed “Blood Deficiency Sputum Disturbance of TCM Syndrome Scale” and “SF-36 Quality of Life Scale” The evaluation evaluated the quality of sleep,TCM syndromes,and quality of life before,after,and at follow-up in each group of patients,and observed the effects of treatment and the duration of efficacy after drug withdrawal.Results: 1.In the course of treatment,there were 8 cases of shedding in traditional Chinese medicine group and the remaining 52 cases,11 cases of western medicine group shedding,and the remaining 49 cases.The joint group was shed 11 cases and the remaining 49 cases.A total of 150 cases entered the statistics.2.After statistical analysis,the symptoms of insomnia in traditional Chinese medicine group after treatment were statistically different from those before treatment(P<0.05),pale face,dizziness,headache,palpitation,fatigue,numbness,Chest tightness,upset,nausea,tongue image,pulse and total scores were significantly different from those before treatment(P<0.01);Western medicine group(2)had paleface,dizziness,headache,chest tightness,upset,tongue,There was no statistical difference between pulse and pre-treatment(P>0.05),and there was a statistically significant difference between nausea and total score before and after treatment(P<0.05).There was statistically significant difference in palpitation,fatigue,and numbness between hands and feet before treatment.P<0.01);The distribution of all syndromes and total scores in the combined group was significantly higher than before treatment(P<0.01).There was no significant difference in sleeping time and sleep disorders between the Chinese medicine group and the patients before treatment(P>0.05).The P values of other items and total scores were <0.01,which was significantly different from that before treatment.Western medicine group There was no statistical difference between hypnotic drugs,daytime function and treatment(P>0.05).The P values of the other sub-items and total scores <0.01 were significantly different from those before treatment;all sub-items and total scores of the combined group were P-values.There was a statistically significant difference between <0.01 and before treatment.In terms of quality of life improvement,there was no statistical difference in the distribution of physiological function of the three groups after treatment compared with that before treatment(P>0.05),and the P value of the remaining dimensions and total score were <0.01,which was significantly different from that before treatment..3.Through the comparison of efficacy evaluation,the total effective rate of total clinical efficacy of the three groups was 88.7%,the effective rate of the Chinese medicine group was 80.8%,the effective rate of the western medicine group was87.8%,and the effective rate of the combined group was 98.0%;The total effective rate of syndrome effect was 88.7%,the effective rate of Chinese medicine group was90.4%,the effective rate of western medicine group was 81.6%,the effective rate of combined group was 93.9%;the total effective rate of sleep quality was 86%,and the sleep quality of Chinese medicine group was effective Up to 76.9%,Western medicine group sleep quality efficiency reached 89.8%,combined group sleep quality efficiency to 91.8%;quality of life to improve the total efficiency to 81.3%,Chinese medicine group efficiency to 73.1%,Western medicine group efficiency to 77.6%,The combined group has an efficiency of 93.9%.Conclusion: Modified AnHun Decoction and Estazolam Tablets are effective in the treatment of blood insomnia and senile insomnia and can improve the quality of life of patients.However,Chinese and Western medicine groups have their own advantages and disadvantages.The western medicine group is superior to the Chinese medicine group in improving sleep quality.The Chinese medicine group has good results in improving patients’ TCM syndromes,mental status,and daytime dysfunction;the combination group has improved sleep quality,TCM syndrome efficacy,and quality of life.The efficacy of the improvement was significantly better than that of the single treatment group.Through the follow-up results,the long-term efficacy of the Chinese medicine group is superior to the Western medicine group,and the long-term efficacy of the combination group is the best and the condition is not easy to repeat.Therefore,patients with mild insomnia but poor overall function are recommended to use Modified AnHun Decoction;Patients with severe insomnia but with overall function are recommended to take oral esmolol tablets;Patients with severe insomnia and poor overall function recommend Chinese and Western medicines Joint use.