| Objective:To observe the clinical effect of medicine-separated moxibustion on the treatment of Diarrhea-type Irritable Bowel Syndrome,and the effect of this method on serum 5-HT level of patients.Methods:Divide 60 patients,who meet the inclusion criteria,into treatment group and control group with every 30 patients,according to randomized control principle.treatment group adopted the method of medicine separated moxibustion,the acupoints selected ZhongWan,TianShu(double),Guan Yuan,ShangJuXu(double),the acupoints in the control group were the same as those in the tetreatment group,the control group was treated with the method of bran separated moxibustion,two groups were treated for 4 weeks,to observe the end of the two groups before and after treatment the serum level of 5-HT,the main symptom score and quality of life scale(IBS-QOL)score change.The data obtained using SPSS20.0 software for statistical analysis.Result:1.Main symptom aspects:the main symptoms of the two groups after treatment score and total score were lower than those before treatment(P<0.01),and the treatment group compared with the control group after treatment:abdominal pain or discomfort,abdominal distension and diarrhea score were decreased more significantly than in the control group,the difference has statistical significance(P<0.05);two groups were improved in patients with abdominal pain or discomfort,abdominal distension,diarrhea and other symptoms,and the treatment group in improving patients with abdominal pain or discomfort,abdominal disten-sion,diarrhea curative effect more pronounced effect than the control group.2.Quality of life scale:the quality of life scale of two groups after treatment(IBS-QOL)score were higher than before treatment(P<0.05),and the treatment group after treatment IBS-QOL score increased significantly compared with the control group,the results were statistically significant(P<0.05),indicating that the two groups can improve the quality of life of patients.And the treatment group in improving the quality of life of patients than in the control group have the advantage.3.Serum 5-HT:the content of serum 5-HT in the treatment group was significantly lower than that before treatment(P<0.01),the control group after treatment,serum 5-HT levels compared with before treatment,the results showed no statistically significant(P>0.05),and between the two groups after treatment,the results have significant differences statistical significance(P<0.01).The treatment group could reduce the level of serum 5-HT in the patients after treatment,but the control group had no significant effect on the serum 5-HT level.4.Overall efficacy:the total effective rate of the treatment group was 86.67%,and the total effective rate of the control group was 72.41%.The difference between the two groups was statistically significant(P<0.01),indicating that the drug separated moxibustion was superior to the control group in improving the symptoms of diarrhea predominant irritable bowel syndrome.Conclusion:The method of medicine separated moxibustion is effective in the treatment of diarrhea-type irritable bowel syndrome,which can improve the clinical symptoms,improve the quality of life of patients,and significantly reduce the serum 5-HT level.This method is a safe and effective treatment. |
PDF Full Text Request