Clinical Observation On The Treatment Of Qi And Yin Deficiency Type Of Chronic Glomerulonephritis By Combined Anti-rheumatism Therapy

PurposeBy observing the observation group and control group before and after treatment and 24 hours urinary protein quantitative,urine sediment red blood cells,the change of the TCM symptom integral,objective to observe the effect of The combined anti-rheumatism of shenqi dihuang decoction on chronic glomerulonephritis of Qi Yin deficiency type.MethodsA randomized controlled trial was carried out to randomly divide 73 patients with Qi and Yin Deficiency Type of chronic glomerulonephritis,which met the requirements of the project,into 36 patients and 37 patients in the control group.The control group was treated with astragalus decoction,and the observation group was combined with anti-rheumatism prescription on the basis of treatment of the control group,and the treatment period was 12 weeks.To observe the changes of urinary sediment concentration,24-hour urinary protein quantification and TCM symptom integral.etc.,and compare the clinical efficacy between the observation group and the control group.Results1.A total of 73 samples were included,37 were observed in the observation group and 36 in the control group.1 case of observation group failed to review on time due to moving to the field,1 case failed to take the medicine as required,and 1 case in the control group was not reviewed on time due to long-term absence,and the above 3 patients were deleted after the telephone contact was invalid.In the end,70 cases were completed in this study,35 in the observation group and 35 in the control group,and the shedding rate was 4.11%.2.There was no statistically significant difference between the two groups in terms of gender,age,course of disease,TCM symptom integral,and laboratory indicators(P>0.05),which was comparable.3.After the treatment of the observation group,the quantitative and 24-hour urinary protein quantification of urinary sediment was significantly decreased compared with that before treatment(P<0.05),and the TCM symptom integral was significantly reduced(P<0.05).The quantitative and 24-hour urinary protein quantification of urinary sediment after treatment in the control group was significantly decreased(P<0.05),and the TCM symptom integral was significantly reduced(P<0.05).4.The effective rate of chronic glomerulonephritis in the observation group and the control group was 91.42%and 57.14%,respectively,and the difference was statistically significant(P<0.05).5.The total effective rate of TCM symptom integral in the observation group and the control group was 85.71%and 80.00%respectively,and the difference was not statistically significant(P>0.05).6.1n the process of observation,all patients had no adverse reaction,the collected blood routine,liver and kidney function and electrocardiogram examination laboratory indexes such as no obvious changes,there was no statistically significant difference before and after treatment comparison(P>0.05)Conclusion1.The combined anti-rheumatism of shenqi dihuang decoction can significantly reduce the urinary sediment concentration and 24-hour urinary protein quantification in patients with chronic glomerulonephritis in patients with chronic glomerulonephritis,and superior to the control group.2.The combined anti-rheumatism of shenqi dihuang decoction can significantly reduce the TCM symptom score of patients with chronic glomerulonephritis,but there is no significant difference with the control group.3.The combined anti-rheumatism of shenqi dihuang decoction did not find obvious adverse reactions,and the safety was good.