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For Differences In The Diagnosis And Clinical Value Of Less Than 3cm Ground-glass Pulmonary Nodules Of Different Reconstruction Of MSCT

Posted on:2019-01-21Degree:MasterType:Thesis
Country:ChinaCandidate:T ChenFull Text:PDF
GTID:2334330548453880Subject:Clinical medicine
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Objective:Explore the different reconstruction methods of MSCT(ie,the specific settings of reconstruction parameters)for the qualitative diagnosis of pulmonary nodules within 3 cm and its clinical value.Methods:Retrospective analysis of imaging features of Sir Run Run Shaw Hospital of Zhejiang University and the Ningbo People's Hospital 136 cases of pulmonary ground-glass nodules.The lung windows with different reconstruction parameters under the two(usual)artificial conditions were defined as a-window reconstruction and?-window reconstruction,and the differences in diagnosis between CT a-window reconstruction and ?-window reconstruction of lung-ground nodules were analyzed and compared.The CT signs of lung-ground nodules with different diagnostic results were further compared.Results:A total of 56 benign nodules were diagnosed,20 were inflammatory lesions,36 were atypical adenomatous hyperplasia(AAH),80 were malignant lesions,35 of which were adenocarcinoma in situ(AIS),25 patients Invasive adenocarcinoma(MIA),the remaining 20 cases of invasive adenocarcinoma(IAC).The diagnostic conclusion of lung nodules obtained by CT? window reconstruction method is more reliable and worthy of clinical application.The diagnostic accuracy of this method is 96.32%.The coincidence rate of benign lesions was 94.64%,and the coincidence rate of malignant lesions was 97.50%.The corresponding sensitivity,specificity,positive predictive value,and negative predictive value were 96.36%,96.30%,98.49%,and 91.37%,respectively.In addition,the CT signs of lung pathology in different pathological types were statistically significant(p<0.05),and the corrected test level(p=0.008).AAH,AIS,MIA,IAC were compared between the four groups.In addition to the pleural depression,the difference between the AAH and IAC in each group was statistically significant.Significant differences in lobectomy sign,burr sign,pleural sign,and vacuolar sign between AAH and MIA.Significant differences in lobectomy sign,burr sign,clear margin,vacuolization sign,blood vessel thickening sign,and vascular convergence sign between the AIS and IAC groups.There was a statistically significant difference between the AIS group and the MIA group in terms of lobulation sign and burr sign;marginal clearness was statistically significant between the MIA and IAC groups.There was a positive correlation between the size of lesions and the number of solid components and benign and malignant lesions,with statistically significant differences(p<0.01).Inflammation,atypical adenomatoid hyperplasia(AAH),and adenocarcinoma in situ(AIS)do not contain solid components.The solid component of invasive adenocarcinoma(IAC)was significantly larger than that of micro-invasive adenocarcinoma(MIA).There was a statistically significant difference between the two(P<0.01).Conclusion:The CT signs of pulmonary ground-glass nodule(GGN)are closely related to its pathological type.Choosing the appropriate reconstruction algorithm can obtain a CT image of lung GGN that is closer to the pathological changes,and the corresponding diagnostic diagnosis rate is higher.This is worthy of clinical application.
Keywords/Search Tags:Multi-slice spiral CT, Ground-glass pulmonary nodules, Qualitative diagnosis, Reconstruction, Tomography, X-ray computed
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