Correlation Research On Pulmonary Embolism Assessment With Dual-source And Dual-energy CT Pulmonary Embolism Index And Pulmonary Perfusion Defect Index

Objective :To access the correlation and consistency of pulmonary embolism index derived from dual-source and dual-energy CT pulmonary angiography(CTPA)and pulmonary perfusion defect index derived from lung perfusion blood volume(PBV)in patients with pulmonary embolism.Methods : patients who were confirmed with pulmonary embolism accepted dual-source and dual-energy CT pulmonary angiography;the work station processed the data and obtained pulmonary artery vessel image and dual energy perfusion image(DEPI);two older doctors separately and independently accessed the CTPA image and DEPI image and conducted index calculation;person correlation analysis and Bland-Altman consistency analysis were separately conducted toward the doctors’ measured data,pulmonary embolism indexes and pulmonary perfusion defect indexes.Then,the average number of the doctors’ measure indexes was selected to conduct person correlation analysis and Bland-Altman consistency analysis toward pulmonary embolism index and pulmonary perfusion defect index of central type pulmonary embolism and peripheral pulmonary embolism.Results :The correlation coefficient of Doctor 1’s measured pulmonary embolism index and pulmonary perfusion defect index was 0.831 and the consistency mean(average number of the deviation)was 3.2;the correlation coefficient of Doctor 2’s measured pulmonary embolism index and pulmonary perfusion defect index was 0.843 and the consistency mean was 3.2;the correlation coefficient of Doctor 1’s and Doctor 2’s pulmonary embolism index was 0.997 and the consistency mean was 0.3;the correlation coefficient of Doctor 1’s and Doctor 2’s pulmonary perfusion defect index was 0.993 and the consistency mean was 0.4;the correlation coefficient of pulmonary embolism index and pulmonary perfusion defect index for central type pulmonary embolism was 0.86 and the consistency mean was 6.9;the correlation coefficient of pulmonary embolism index and pulmonary perfusion defect index for peripheral pulmonary embolism was 0.863 and the consistency mean was 0.2.Conclusion :Pulmonary embolism index possesses high correlation with pulmonary perfusion defect index;both of them are able to quantify the degree of pulmonary embolism.However,the difference exists in the consistency of the pulmonary embolism index and the pulmonary perfusion defect index for the central type pulmonary embolism.Thus,both of them shall be combined to comprehensively access pulmonary embolism illness degree clinically.