The Value Of FFR In Interventional Therapy Of Coronary Heart Disease

Objective: To explore the clinical application of coronary angiography versus FFR for guiding percutaneous coronary intervention with coronary artery disease.Methods : Select the First Affiliated Hospital of Xinjiang Medical University Heart Center from January 2016 to January 2018 in patients with coronary heart disease,Coronary angiography(CAG)showed that the degree of coronary artery stenosis was 70%-90%,and the Effective blood vessels,diameter was more than 2.5mm,finally selected 82 patients(146 lesions),divided into two groups,including the observation group(FFR group)had 40 cases(72 lesions),All patients underwent FFR measurement,and FFR guided percutaneous coronary intervention(PCI),a total of 42 patients(74 lesions)in the control group(CAG group)underwent coronary angiography guided percutaneous coronary intervention(PCI).Comparing and analyzing the baseline data of patients,the number of stent implants,hospitalization costs,the number of vascular lesions and the MACE events which were followed up for six months in two groups.Results: FFR group and CAG group had no statistically significant differences in age,gender,basic diseases(including type 2 diabetes,hypertension),BMI,smoking,and blood lipid levels(P>0.05).Compared with the CAG group,the number of scaffolds in the FFR group was significantly lower than that in the control group [(0.88 ± 0.88)vs(1.81 ± 0.80),P <0.05],and lower hospitalization costs [(4.72 ± 2.30)vs(6.00 ± 2.41)ten thousand,P<0.05].The main adverse cardiovascular events(cardiovascular all-cause mortality,recurrent angina pectoris,revascularization rate and the rate of recurrent myocardial infarction)in the FFR group and the C AG group after coronary stent implantation(0.00% vs 0.00%,2.50% vs 0.00%,2.50% vs 2.38%,5.00% vs 7.14%).The difference was not statistically significant(P>0.05).Conclusions :1.The 6-month follow-up of the selected patients showed that FFR-guided PCI did not increase the incidence of cardiovascular major adverse events compared with stenting-guided PCI under coronary angiography.The treatment was safe and effective.2.When the same number of coronary lesions when FFR-guided PCI treatment can significantly reduce unnecessary stent implantation,so that less postoperative stent thrombosis incidence.3.The FFR-guided PCI group significantly reduced medical costs,thereby alleviating the patient's financial stress to a large extent and also meeting immediate medical insurance policy requirements,thereby reducing our financial expenditure.