Clinical Analysis Of Moderate And Severe OSAHS Treated By CPAP And BiPAP

Objective:To investigate the clinical effects of continuous positive airway pressure(CPAP)and bi-level positive airway pressure ventilation(Bi PAP)in the treatment of moderate and severe obstructive sleep apnea-hypopnea syndrome Efficacy.Methods: We retrospectively analyzed the clinical data of polysomnography(PSG)monitoring performed at the Second Hospital of Lanzhou University from July 2015 to December 2017 and diagnosed with moderate to severe OSAHS.The age,sex,BMI,and changes in PO2,F EV1%pred,and FEV1/FVC before and after treatment with CPAP and Bi PAP were studied according to the severity of the patient's condition and the ventilation pattern of the treatment.Results:1.33 patients with moderate OSAHS.There are 31 males and 2 females.Between the ages of 32-80 years old,the average age is 52.55±11.42 years old.The BMI is between 26.3-30.51 kg/m2 and the average BMI is 29.22±1.1 kg/m2.Among them,15 patients received CPAP mode of treatment.The average PO2 before treatment was 55.07±3.15 mm Hg,and the mean value after treatment was 62.60±1.99 mm Hg.The mean value before FEV1%pred treatment was 69.32±3.80,and the average after treatment was 71.30±3.67.The mean pre-treatment FEV1/FVC(%)was 66.85±1.98,and the average after treatment was 68.17±1.92.Eighteen patients received Bi PAP mode therapy.The average PO2 before treatment was 49.78±3.30 mm Hg,and the average after treatment was 58.33±5.43 mm Hg.The mean value before FEV1%pred treatment was 56.06±3.93,and the average after treatment was 59.13±4.37.The pre-treatment average of FEV1/FVC(%)was 57.85±3.88,and the average after treatment was 62.00±3.85.2.There are 38 patients with severe OSAHS.There are 34 males and 4 females.The patients were between 29 and 65 years of age with an average age of 51.84 ± 9.85 years.The BMI is between 30.55-38.77 kg/m2 and the average BMI is 32.83±1.67 kg/m2.Among them,17 patients received CPAP treatment.The average PO2 before treatment was 44.48±9.98 mm Hg.The mean value after treatment was 53.82±5.64 mm Hg.The mean value before FEV1%pred treatment was 49.44±1.49,and the average after treatment was 58.97±1.73.The mean value of FEV1/FVC(%)before treatment was 50.83±1.41,and the average after treatment was 61.97±1.74.21 patients received Bi PAP treatment.The average PO2 before treatment was 44.38±2.11 mm Hg,and the mean value after treatment was 53.71±5.16 mm Hg.The mean value of FEV1%pred before treatment was 38.45±8.22,and the mean value after treatment was 54.02±3.78.The mean pre-treatment FEV1/FVC(%)was 41.99±5.80,and the average after treatment was 56.40±3.13.Conclusion:1.The BMI of patients with severe OSAHS was significantly higher than that of patients with moderate OSAHS.Therefore,the higher the BMI of patients with OSAHS,the greater the likelihood of having severe disease.2.Moderate OSAHS patients can significantly improve the patients' PO2 through the CPAP model.Bi PAP therapy can significantly improve patients' PO2,FEV1%pred,and FEV1/FVC.The effect of Bi PAP mode to improve PO2 is better than that of CPAP mode.3.Patients with severe OSAHS can significantly improve PO2,FEV1%pred,and FEV1/FVC after treatment with CPAP and Bi PAP.The effect of improving PO2 after CPAP mode and Bi PAP mode was equivalent;after treatment with Bi PAP mode,FEV1%pred and FEV1/FVC were better than CPAP mode.