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The Potential Application Of Electrospinning To Prepare Micro-nanofibers In The Field Of Wound Dressings And Textile Garments

Posted on:2018-05-08Degree:MasterType:Thesis
Country:ChinaCandidate:L WangFull Text:PDF
GTID:2351330533961950Subject:Physics
Abstract/Summary:PDF Full Text Request
Nanotechnology has becomeone of the representatives science and the forefront of technology in the 21 st century.Besides,it played a vital role in the developmentof socio-economic,which has attracted more and more global scientists' attention.The nanofibers is the ultrafine fibers having a diameter less than 100 nanometers and it alsocan be extended to modified fibers which are filled with nanoparticles.The properties of nanofibers are closely related to their structure,so nanofibers exhibited different effects from macroscopic materials,such as surface effect,small size effect,quantum size effect,macroscopic quantum tunneling effect.The method for preparing nanofibers mainly included molecular technology(arc discharge method,laser ablation method and fixed bed catalytic cracking method),biological method and electrospinning.Due to the convenient setup,wide selection of raw materials and simple operation,electrospinning draw more attention.The preparation of micro-nanofibers by electrospinning is mainly related to the following parameters,such as the nature of the solution,the environmental factors and the parameters in the electeospinning process.The nanofibers prepared by electrospinning have been widely used in the field of photoelectric sensors,environmental protection and biomedicine.The second chapter mainly introduces the electrospinning composite nanofiber membrane as wound dressing for scar treatment.PCL has excellent mechanical properties and good biocompatibility,which has be used as drug-controlled carrier and tissue culture scaffold.Gelatin is natural polymer materials without fixed structure.And it degraded by animal skin,bone,muscle charm and other connective tissue,which has been widely used in food and medicine.The composite nanofibers as a carrier for small molecule drugs for wound dressings.The mechanical properties of PCL complement the lack of gelatin,and the hydrophilicity of gelatin effectively improves the biological properties of nanofibers membranes.The porous structure of the composite nanofibrous membranes is similar to the extracellular matrix,which can promote cell migration and proliferation.Through the construction of animal model,it was observed that the composite nanofibers membranes loaded small molecule drug as wound dressing could effectively reduce the scar formation and achieve the effect of treating scar in wound healing process.In the third chapter,we introduce a new solvent-free electrospinning to prepare colorful micro/nano-fibers.In the process of traditional electrospinning,polymer has to dissolve or disperse into a large number of organic solvent,which releases volatile organic to thesurrounding.At the same time,organic solvent will cause environmental pollution and do harm to the operator.In addition,colorful textiles are generally obtained by printing and dyeing.During the printing and dyeing,dye has to dissolve into a medium solution,and using the combination of dyes and fiber to produce the colorful textiles in the condition of high pressure and high temperature.It is difficult to recycle the high-pressure steam and high concentrations of dyes in the effluent.The fade oftextiles is another big problem.Therefore,make use of a new solventless electrospinning to produce colorful fibers can effectively avoid the above problems.The parameters of micro/nano-fibers prepared by electrospinning are optimized,and the color of fibrous membranes is adjustable.The twisted fibrous rope prepared by membranes has good thermal stability,excellent tensile properties and color stability,and explored its broad application prospects in the field of textile and clothing.
Keywords/Search Tags:Electrospining, wound dressings, solventless, colorful fibers
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