Study On The Distribution Of TCM Syndrome Types And Related Factors In Early Renal Damage Of Hypertension

ObjectiveResearch on the relationship between TCM Syndrome Types of Early Renal Damage in Essential Hypertension and early renal function,Cystatin C and 24 Hour Ambulatory Blood Pressure,in order to provide the basis for the TCM syndrome type of the disease and the syndrome differentiation and treatment of objective study,improve the clinical early diagnosis.Study on the correlation between the disease of TCM syndrome type and weight index,age distribution,to provide the evidence for the prevention and control of the disease.Methods200 cases were diagnonsed renal damaged hypertension patients,medical history data of patients,The main TCM syndrome type follows:Qi deficiency and Phlegm Blood Stasis Syndrome,hyperactivity of Yang due to yin deficiency syndrome,kidney deficiency and blood stasis syndrome,hyperactivity of liver yang.patients in each group were recorded as general data,early renal function,serum cystatin C,24 Hour Ambulatory Blood Pressure Monitoring,then input these clinical data,statistical and analysis respectively with SPSS 17.0.Results1.To compare TCM syndrome type and cystatin C:90 cases (45%) index are normal and 110 cases (55%) are abnormal,this is suggested that cystatin C has better reference value for the early renal damage of hypertension,but there is no statistical significance difference between four types of syndrome (P>0.05).2.To compare TCM syndrome type with early renal function:the index of urine alpha 1-M increased between four types of syndrome, there is statistical significance difference between four types of syndrome(p<0.05);But the index of mALB,TRU, IgG no difference (P>0.05).But from the trend we can tell that:?the deficiency of Qi and stagnation of phlegm and blood stasis,yin deficiency and yang hyperactivity syndrome:the three detection levels were elevated.?The indexes of TRU,IgG were elevated in the syndrome of deficiency of kidney and blood stasis,but mALB and TRU levels elevated in the syndrome of hyperactivity of liver Yang.3.Compare TCM syndrome type with 24h ambulatory blood pressure levels:?the rank frequency distribution:blood pressure level distribution between groups had no statistical difference.?The pulse pressure,mean systolic pressure,mean diastolic pressure:the result of hyperactivity of liver yang is maximum,qi deficiency and blood stasis of is minimum,there are statistical significance (P=0.00)among various types.? The systolic pressure coefficient of variation:Qi deficiency with phlegm and blood stasis syndrome is maximum, hyperactivity of liver yang is minimum,there are statistical significance (P<0.05)among four types.Diastolic blood pressure coefficient of variation:Qi deficiency and Phlegm Blood Stasis Syndrome is maximum,yin deficiency and yang hyperactivity is minimum,there are no statistical significance between four syndrome.Conclusion1.The main TCM syndrome type of 200 cases follows:Qi deficiency and Phlegm Blood Stasis Syndrome,hyperactivity of Yang due to yin deficiency syndrome,kidney deficiency and blood stasis syndrome,hyperactivity of liver yang.2.These index levels,include Cystatin C,urinary alpha 1-M,mALB, TRU, IgG have statistics differences in four types,this can be used as reference index of TCM syndrome differentiation and treatment evaluation.3.24h ambulatory blood pressure as the most important essential hypertension detection and inspection methods, their parameters detected between the four syndromes have differences, can be used as an adjunct to diagnosis and treatment of essential hypertension medicine.