Retrospective Analysis Of Early Postoperative Prognosis In Children With Complex Aortic Malformation By Combined Heart And Brain Perfusion And Simple Regional Cerebral Perfusion

Objective:To investigate and evaluate the application of cerebral and myocardial perfusion(CMP)and only-regional cerebral perfusion(only-RCP)in pediatric complicated aortic surgery.Methods:From 2011 to 2014,one hundred and forty one children with CoA or IAA combined with cardiac defects such as VSD or ASD undergoing one-stage corrective surgery were included in this study.They were divided into two groups,CMP(n=56)and only-RCP(n=85),based upon the CPB strategy.The surgery and CPB parameters,postoperative biochemical index,recovery situation,and postoperative complications were recorded and compared between two groups.Results:The bypass time,arrest time,operative time,cardiac ischemia time,and the length of hospital stay and respiratory support time in CMP group are significantly shorter than those in only-RCP group.And the level of biochemical index which can reflect the function of liver and kidney in CMP group also lower than those in only-RCP group.Conclusion:The modified perfusion strategy of CMP could provide better prognosis for children undergoing one-stage aortic arch surgery,and may reduce the length of hospital stay and the respiratory support time.