Systematic Evaluation Of The Efficacy Of Traditional Chinese Medicine Retention Enema In The Treatment Of Acute Pancreatitis

Purpose: Based on traditional Chinese medicine retention enema in treatment of acute pancreatitis randomized controlled trial(RCT)clinical curative effect evaluation and objective evaluation of traditional Chinese medicine retain enema in the treatment of acute pancreatitis,traditional Chinese medicine for the treatment of acute pancreatitis to provide evidence of evidence-based medicine.Registry platform will PROSPERO system evaluation of traditional Chinese medicine resources,summarized the status quo,to improve the quality of the registered rate of traditional Chinese medicine researchers and registration,to promote the development of traditional Chinese medicine research in the field of international evidence-based medicine.Material and method:Registration by PROSPERO system evaluation platform,USES The evaluator Cochrane handbook system evaluation method is introduced,retrieve The Cochrane library,Medline,Embase,SCI,CNKI,Wangfang data,CBM and VIP database study of traditional Chinese medicine enema in The treatment of acute pancreatitis,main indicators: abdominal pain,abdominal distension relief time;Independent defecation time;Serum amylase returned to normal time,and the secondary indexes,CRP returned to normal time.Improved Balthazar CT score and APACHEII scores;Complications were system evaluation as evaluation index,USES the Cochrane collaboration system evaluation software Rev make Man 5.1 the study of finally filter into this system to evaluate accurately the Meta-analysis.PROSPERO system evaluation registered platform by December 2016,summarized the status quo analysis of traditional Chinese medicine resources.Results: 1.Chinese medicine retention enema in alleviating abdominal pain symptoms of acute pancreatitis,early intestinal function recovery in acute pancreatitis,reduce serum amylase value and lower the APACHE II score obvious effects in time.2.This study included in all clinical trials are conducted to the randomized method,but for allocation concealment and blinding,exit and the description of the lost to follow-up is very limited,do not rule out there is the possibility of selection bias and measurement bias.3.PROSPRO platform registered potential for research of traditional Chinese medicine resources,in terms of topic selection can choose medicine,Chinese medicine syndrome differentiation combined oral western medicine,Chinese medicine enema and apply patches in the study of interventions.Conclusion: 1.Chinese medicine retain enema combined western medicine support support treatment curative effect is superior to western medicine therapy and western medicine treatment + warm soapy water enema solutions,as a high-level evidence-based medical evidence to provide research data for acute pancreatitis guide.2.The system evaluation research plan represented by PROSPRO platform registration is to improve the quality system evaluation,essential steps to promote the development of evidence-based medicine.