Study On Syndrome Elements Of Hepatitis Cirrhosis Based On Implicit Structure Method

Objective:To explore the common syndrome elements of hepatitis cirrhosis,establish the identification criteria for common syndrome elements of hepatitis cirrhosis,provides supplements and evidence for clinically accurate identification of syndromes,and promotes objectivity and modernization of clinical differentiationMethods:Using the "Clinic Information Collection Table for Hepatitis Cirrhosis" prepared by the research group in the earlier period,we collected four diagnostic information(symptoms and signs)from 801 patients with hepatitis cirrhosis.This study screened 97 symptoms and signs with a frequency of>10%.The correlation analysis of 97 symptoms and signs was performed using the latent class analysis method.Combined with the basic theories and clinical experience of traditional Chinese medicine,common disease-like syndrome elements of patients with hepatic cirrhosis were extracted and their identification criteria were established.Result:1.A latent class analysis was performed on 97 symptoms and signs.A total of 35 latent variables and 77 subtypes were obtained.802 common symptoms of cirrhosis were extracted:qi deficiency,wetness,heat syndrome,Yin deficiency,blood stasis syndrome,Yang deficiency,qi stagnation syndrome,Water-stagnation syndrome.2.Through the analysis of the latent class of the syndrome elements of common cirrhosis caused by hepatitis,preliminary identification criteria:Qi deficiency(threshold:8.4):lazyness(5.4),fatigue(5.1),Shenfa(4.1),diarrhea(1.7),stool(1.2),dull complexion(1.0),spontaneous perspiration(0.8),pale tongue(0.9),pale complexion(0.6);wetness(threshold:14.1):thick moss(20.4),Decomposed moss(3.4),Jaundice(0.8),Fat tongue(0.7),Tired greasy(0.6),Teeth(0.4),Nausea(0.3),Mouth sticky(0.3);Heat syndrome(Threshold:5.6):Oral bitterness(4.5),Oropharyngeal dryness(4.1),Deep yellow urine(3.0),Thirst(2.9),Dry/brown moss(2.4),Fever(2.3),Constipation(2.1),Red tongue(1.5),old tongue(1.5),Huamai(0.9),several pulses(0.8);yin deficiency(threshold:6.0):dry skin(4.3),oropharyngeal dryness(4.1),tinnitus(4.1),Eyes fainted(3.9),thirsty(3.2),blinded(2.8),cracked tongue(2.8),night sweats(2.8),conscious fever(2.2),thin tongue(2.0),blood stasis syndrome(threshold value:7.2:Abdominal varicose veins(3.7),Dermal nailing errors(1.8),Sublingual collaterals abnormality(4.5),Spider webs(2.0),Black complexion(2.3),Freckle/click tongues(7.4),Dull complexion(2.6),Spleen enlargement(2.1);Yang deficiency(threshold:5.6):Five more diarrhea(4),nocturia more(3.3),Yaoxisuanruan/waist and knee pain(2.7),lumbar cold(2.1),fear Coldness(2.0),Endless Valley(2.0),Loss of Sexual Desire(1.8);Qi stagnation syndrome(threshold:6.8):Trek(4.0),Depression(3.1),Throat(2.2),Hypotensive(1.9),Gastric fistula fullness(1.7),bloating(1.1),Xuan mai(0.3);Water-stagnation syndrome(threshold:3.7):slippery fur(4.1),ascites(1.4),reduced urine volume(1.3),edema(1.2).Conclusion:1.Through the analysis of the information on hepatitis cirrhosis four clinics,we extracted 801 common syndromes of cirrhosis patients:Qi deficiency syndrome,wet syndrome,heat syndrome,yin deficiency syndrome,blood stasis syndrome,and yang deficiency syndrome.Cards,qi stagnation cards,and water stop cards indicate that these syndrome elements are common clinical syndrome elements.2.The identification criteria of the common etiological elements of hepatitis cirrhosis were established by the hidden structure analysis method.It was found that the hidden structure method is more suitable for the analysis of syndrome elements.