| Research purposes By collecting the patients of coronary heart disease(CHD)to merge the cerebral infarction(CI)as experimental group,and the patients of Cl as control group,explore the syndrome factor distribution and the clinical research on traditional Chinese medicine(TCM).Significance1.Explore the similarities and differences between the two syndromes through the exploration of the distribution of the two syndromes,so as to explore the differences between the two pathogenesis.2.By analyzing the similarities and differences between the two drugs,it is helpful to summarize the differences and similarities between the two groups,so as to explore the rule of TCM in the treatment of atherosclerotic cardiovascular and cerebrovascular diseases(ASCCVD).Research methods1.Based on CNKI database(2001-2001)and atherosclerosis(AS)related literature research,"Syndrome Factor Differentiation Discipline" for reference,combining with the related factor in this study include symptoms as a table,and the Chinese medicine new medicine clinical research guiding principles of Cl and CHD,and refining the symptoms point of two kinds of disease and eventually made into" symptoms-syndrome factor clinical questionnaire ".2.This study is a prospective study,from Beijing university of Chinese medicine DongZhiMen hospital on January 1,2017-on October 31,2017 in the hospital ward who was diagnosed coronary heart disease merging the cerebral infarction disease(HCD)as experimental group,and the CI as control group.3.The raw data was quantized and processed into computer,and SPSS 20.0 statistical software was used for medical statistical analysis.The distribution of TCM syndrome in the experimental group and the control group was summarized,and the regularity of the two drugs was explored,and the difference of the two drugs was explored.ResultsThis study on the pathological basis of atherosclerosis,from the pespective of TCM syndrome factor and drug use,on the analysis of two pathological changes of two groups in atherosclerosis disease(HCD and CI),and to explore the pathogenesis of the similarities and differences,aims to study pathogenesis development of AS disease in TCM.On the other hand,through the analysis of the similarities and differences of the two groups in herbs,it is useful to summarize their similarities and differences,and embodies idea of "sputum-blood stagnation treatment".(1)1.The high frequency syndromes of the HCD are:heart,Yin deficiency,liver,qi deficiency,blood stasis,phlegm;blood deficiency,qi stagnation,meridian,humidity,Yang deficiency,kidney,Yang kang,spleen 14 kinds of syndrome.2.The high frequency syndrome of CI is liver,Yin deficiency,meridian,phlegm,dampness,blood stasis,heart,qi deficiency,Yang kang,qi stagnation,dynamic wind,heat and blood deficiency.3.The two groups of the same high frequency have the heart,Yin deficiency,liver,qi deficiency,blood stasis,phlegm,blood deficiency,qi stagnation,meridian,wet,Yang kang.4.The results showed that there was no significant difference between CI and HCD in Yin deficiency,liver,blood stasis,phlegm,wet,yangon,spleen and muscle.There are obvious differences in heart,qi deficiency,blood deficiency,qi stagnation,Yang deficiency,kidney,meridian,dynamic wind and heat.In the six syndromes of heart,qi deficiency,blood deficiency,qi stagnation,Yang deficiency and kidney,HCD was significantly larger than CI,while CI was greater than HCD in the three syndromes of meridian,dynamic wind and heat.(2)1.The high-frequency medication of HCD is BaiZhu,FuLin,QingBanxia,ChuanXiong,DanGui,ShiChangpu,ChiShao,HuangQi,ShengGancao,TianMa,ChenPi,ChaiHu,HuangQin,BaiShao,GuiZhi,ZhiQiao,GeGeng,HuangLian,Shengjiang,ShengDi.2.The high frequency medication of CI is FuLin,ChuanXiong,DangGui,ChiShao,BaiZhu,HuangQi,DanSheng,ShengGancao,QingBanxia,ShiChangpu,DiLong,ChenPi,HuangLian,TianMa,ZhiQiao,HongHua,GuiZhi,HuangQin,TaoRen,ChaiHu,ShengDi,ShaRen.3.The two groups in the high frequency use common medication are FuLin,ChuanXiong,DanGui,ChiShao,BaiZhu,HuangQi,DanSheng,ShengGancao,QingBanxia,ShiChangpu,ChenPi,HuangLian,TianMa,ZhiQiao,GuiZhi,ChaiHu,HuangQin,ShengDi,which is no difference in the use of the drugs.4.There was a significant difference in the use of the drugs on the DiLong,TaoRen,DuZhong,JiXueteng,HouPo,ZhiShi and GuaLou.(3)HCD at he distribution of four Qi five Tastes,from high to low in the arrangement of frequency,is warm,cold,flat,sweet,bitter,xin,liver,lung,spleen,stomach,colon,bladder,kidney,heart,bladder,while the CI is cold,warm,flat,bitter,gan,xin,liver,spleen,lung,stomach,heart,kidney,large intestine,bladder and gallbladder.There was no significant difference in the distribution of four Qi five Tastes.Conclusion(1)There was no significant difference between the two groups in blood stasis,phlegm,wet,Yin deficiency,liver,spleen and other syndromes.We can conclude that basic pathological basis of HCD and CI is phlegm and blood stasis,the common pathogenesis is liver and kidney Yin deficiency,spleen deficiency phlegm wet endogenous.,"Phlegm and blood stasis" is an important pathologic factor of ASCCVD.(2)On the comparison of the difference of syndrome factor of two groups patients of HCD is rmore than belongs to collaterals stasis,long illness into complex,and more performance for the deficiency of kidney Yang deficiency,blood deficiency,heart and kidney deficiency.In the case of patients of CI,there are many syndromes of hyperthermia and blood vessels,which are characterized by the syndrome of hyperactivity of heat and the accumulation of pathogens.(3)The common management of two groups is to remove blood stasis,clear heat and detoxify,warm and enhance qi,and evacuate liver.The thought of "phlegm-blood stasis treatment" has been used throughout the treatment of ASCCVD.(4)Two groups have different in the use of DiLong,TaoRen,DuZhong,JiXueteng,HouPo,and the CI was more than that of HCD;On the other hand,there were differences in the use of ZhiShi and GuaLou,and HCD was more than that of CI.(5)there was no significant difference between the two groups in the distribution of four Qi five Tastes,which showed that the treatment of ASCCVD was in common with the use of the four qi and five flavors of Chinese medicine. |
