Study On The Rule Of Syndrome Differentiation Of Chaihu Plus Keel Oyster Soup

Objective and significance:Chaihu plus Longgu Muli Decoction is found in Article 107 of Treatise on Cold Damage and Miscellaneous Diseases.Ancient and modern physicians have different opinions on its prescription composition,etiology and pathogenesis.This paper extensively collected relevant literatures on Chaihu plus Longgu Muli Decoction at home and abroad,combed the similarities and differences between ancient and modern physicians'views on formula and syndrome,and summarized the characteristics of syndrome and treatment,and clinical application rules,providing references for the expansion of clinical application.Methods:Linguistic research methods such as Summarization method and frequency analysis method were adopted.Chinese Medical Dictionary software was used as a search tool,and Overview of Treatise on Cold Damage and Miscellaneous Diseases Related Books was referred to literatures on Chaihu plus Longgu Muli Decoction in by Chinese and Japanese traditional medicine,and analyze the characteristics of its syndromes and treatment.Medical cases of clinical application of Chaihu plus Longgu Muli Decoction in the past five years were collected,and its clinical application rule was summarized by frequency analysis method.Results:Firstly,ancient physicians believed that the disease and syndrome factors of Chaihu plus Longgu Muli Decoction were phlegm and shaoyang descending.The disease locations have the heart,diaphragm and sanjiao,and with total of 23 pathogenesis.The abdomen examination was featured as abdominal distension,resistant feeling under the heart,turbulent movements around umbilicus and qi movement ascending to umbilicus and oppressed under the heart.Secondly,currently,the Chaihu plus Longgu Muli Decoction was mainly applied to treat women aged 30-50 years old,with a total of 39 kinds of syndromes involving 11 systems,mainly about mental system(39.08%of the total frequency),nervous system(16.09%of the total frequency),and circulatory system(10.34%of the total frequency).The causes of the disease were mainly internal injuries of seven emotions(68.97%),followed by phlegm(17.24%),and manifested by insomnia,irritability,constipation,and loss of appetite,bitterness in the mouth,emotional depression,chest tightness,palpitations,dry mouth,red tongue,white coating.The commonly used doses in clinical practice are Radix Bupleuri 10g,Os Draconis 30g,Radix Scutellariae 10g,Rhizoma Zingiberis Recens 15g(3 pieces),Radix et Rhizoma Ginseng 10g,Ramulus Cinnamomi 9g,Poria 15g,Rhizoma Pinelliae 10g,Radix et Rhizoma Rhei 3g,Concha Ostreae 30g,Fructus Jujubae 10g(3 pieces).The frequency of added herbs was up to 500,involving 124 kinds of Chinese herbs,and were mainly tonifying deficiency herbs(118 times),calming the minds herbs(78 times),clearing heat herbs(61 times),activating the blood and resolving stasis herbs(48 times).The top 10 frequency of added herbs were Radix et Rhizoma Glycyrrhizae,Radix Paeoniae Alba,Semen Ziziphi Spinosae,Magnetitum,Radix Curcumae,Fructus Aurantii Immaturus,Rhizoma Acori Tatarinowii,Radix Angelicae Sinensis,Rhizoma Chuanxiong,Fructus Gardeniae.Thirdly,although the ancient herbal medicine books recorded that the minium was not toxic,it was applied with low dose(usually no more than 5g).It should be wrapped by gauze and decocted,but it should not be taken for long term.Nowadays,Radix Polygalae,Haematitum,Frusta Ferri,Magnetitum,Concha Margaritiferae Usta,Succinum,Cinnabaris mixed Poria,Concha Haliotidis,Fluoritum,Chlorite-schist,baijin pill,Semen Sinapis were used in clinical practice.Fourthly,ancient and modern literature were summarized and combined with clinical practice.It was found that Daling(PC 7),Taichong(LV 3),Fenglong(ST 40)combined with puncturing blood and adjusting the sinews matched the formula and syndrome characteristics of Chaihu plus Longgu Muli Decoction,which could effectively treat mental or nervous system diseases.Conclusion:The ancient doctors attached importance to theoretical study on original text and formula of Chaihu plus Longgu Muli Decoction,and discuss its pathogenesis from six-channel,eight-principle,yin-wei qi and blood,zang-fu organs,while Japanese traditional physicians mostly described its clinical indications and made up for the main points of abdominal examination.It was especially effective for depression,anxiety,schizophrenia and other mental and nervous system diseases.