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The Research About Protein Microarray Database Building

Posted on:2017-04-06Degree:MasterType:Thesis
Country:ChinaCandidate:Z W XuFull Text:PDF
GTID:2370330590969416Subject:Biology
Abstract/Summary:PDF Full Text Request
Protein microarray is a powerful technology for both basic biology and clinical study.The effectiveness of protein microarray technology has already been well approved by numerous studies in the past decade.However,because there is no database specifically tailored for protein microarray,the majority of the valuable original protein microarray data is still not publically accessible.To address this issue,we constructed Protein Microarray Database(PMD,www.proteinmicroarray.cn),which is specifically designed for archiving and analyzing protein microarray data.In PMD,users can easily browse and search the entire database by experimental name,protein microarray type,and sample information.PMD now accept data from a variety types of protein microarrays,such as proteome microarray,antibody microarray,lectin microarray,and etc.Additionally,to help users who are not familiar with protein microarray technology and protein microarray data processing,several bioinformatics tools have been integrated into PMD for protein microarray data processing and analyzing.With just one click,users can obtain a comprehensive analysis report for their protein microarray data.The report includes preliminary data analysis,such as data normalization,candidate identification,and an in-depth bioinformatics analysis of the candidates,which include functional annotation,pathway analysis,and protein-protein interaction network analysis.The latest high-impact publications about the development and applications of protein microarray technology are actively collected in PMD and open accessible.To our knowledge,PMD is the first specific database for sharing and analyzing the protein microarray data.With PMD,one can access all of the related information and the original protein microarray data in a “one-stop” fashion,with a capability of “one-click” data analysis.We strongly believe that PMD is a valuable resource for the research community by promoting protein microarray data sharing and facilitating data analysis.
Keywords/Search Tags:protein microarray, database, data archiving, data analysis
PDF Full Text Request
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