Research On The Fabrication And Application Of ECL Probes Based On Magnetic Quantum Dot Compound Molecularly Imprinted

At present,more and more attention is paid to the treatment of organic pollutants in the environment.Electrochemiluminescence technology raised a hot research in the study of electrochemical in recent years.This technique,simple operation and high sensitivity,which can be used to detect all kinds of material.But it needs to be improved at specific selectivity,and to be constructed a high selective sensors.Molecular imprinting technology own a wider application range due to its feature of specific recognition target molecules,good stability in the special environment,and obvious adsorption effect.However,the traditional molecularly imprinted polymer have many defect,for example,slow polymerization process,low-affinity of the identify imprinting cavity and the difficulty of elution process.Therefore,the deficiency is restrict to the aspects of its application.Based on this,there are many improved methods have been used for the preparation of novel molecularly imprinted polymer,such as surface molecular imprinting technology,which synthesis of molecularly imprinted polymer in the surface of carrier that can solve the above problems.Based on electrochemiluminescence technology and molecular imprinting technology,this paper have been prepared core-shell structures magnetic quantum dot compound molecularly imprinted polymers,and ECL detection was performed by using electrochemical luminescence properties of quantum dots.The properties of quantum dots have been investigated with fluorescence spectra(FL)and UV-Vis absorption spectroscopy(UV-Vis).Fourier transform infrared spectroscopy(FT-IR),vibration sample magnetometer(VSM)and high resolution transmission electron microscopy(HRTEM)were used to characterize the structure and morphology of different products.The main content shows in as follows:The ECL probe based on core-shell structure magnetic quantum dot compound molecularly imprinted polymer was constructed to detect tetracycline hydrochloride.The core-shell CdTe/ZnS QDs was prepared by hydrothermal method,which is characterized by FL and UV-Vis.Fe3O4 is easy to reunite,but to change its surface property and function easily when it added silane coupling agent on the surface,which can help the formation of composite materials.The polymer by using tetracycline hydrochloride as the target molecule,the functional monomer is methacrylic acid(MAA),the crosslinking agent is ethylene glycol dimethacrylate(EGDMA),the initiator is azo diisobutyronitrile(AIBN),core-shell Fe3O4 nanoparticles as carrier,and add quantum dots to prepare magnetic MIP.The ECL probe based on core-shell structure of magnetic quantum dot compound molecularly imprinted polymer was constructed to detect bisphenol A.The CdSe QDs was prepared by hydrothermal method,which is characterized by FL and UV-Vis.At the surface of core-shell magnetic microsphere to prepare for MIP with add QDs and by using self-polymerization of dopamine to form imprint layer.The well-prepared ECL sensor satisfied in samples detection of BPA with a wider linear range from 10-4 to 10'9 mol L-1 and a lower detection limit of 3.4�10-10 mol L-1(Signal-to-Noise ratio is 3).The proposed ECL sensor displayed highly responsive and stability,and provided an approach for determining other important materials.