Synthesis Of Novel One-dimensional Structured ZIFs Nanomaterials Via Self-templates And Their Applications

Template method has a unique advantage in the synthesis of one-dimensional nanostructured materials.It can not only copy the template structure well,but also be molded into special structure under different conditions,which can be divided into hard template and soft template.The template method has obvious advantages in the synthesis of metal-organic framework materials(MOFs).However,hard template methods,such as Tellurium nanowires,AAO pore size and Carbon nanowires,have been studied in the past.The main disadvantage of this method is the complexity of the steps.If a pure MOF material is obtained after synthesis,further treatment of the sample is needed.As a commonly used soft template,supramolecular self-assembly template is customizable and adjustable in structure with the help of noncovalent bond force between assembly units.In this paper,we use super-molecular self-assembly template,which is easy to synthesize a variety of ZIF-8materials with one-dimensional structure including nanowires,nanotubes,nanobelts and so on.Because of its large porosity,graded pore structure and high specific surface area,ZIF-8has potential application value in drug loading and enzyme catalysis.The main results and conclusions were summarized as follows:1.Using the ZnSC supramolecular self-assembly template,one-dimensional ZIF-8nanomaterials with various morphologies and microstructures have been synthesized at room temperature,including cross-linked nanowires,nanotubes,mesoporous nanobelts and ultra-thin spiral bands.The growth and morphology of the template are controlled by the ratio of mixed solvents and the synthesis of nano-materials depends to a great extent on the relative rate between the formation of metal-organic polymers and ZnSC template dissociation.The morphology and pore structure of ZIF-8 nanomaterials are customizable by changing the macro-reaction conditions,such as the concentration of reactants and the reaction time.This procedure provides a universal methodology to design and fabricate diverse 1D MOFs like ZIF-67,ZIF-7,Zn-Co ZIFs.The synthesized ZIF-8 nanowires can also be used as hard templates to prepare carbon nanofibers by sintering.2.The resutant 1D ZIF-8 nanomaterials have graded pore structure and special high surface area,which can be used to load different drug molecules and biomacromolecules.The porous ZIF-8 nanobelts show the high loading efficiency of Adriamycin hydrochloride(DOX)(280 mg/g).They also represent remarkable slow release characteristics and sensitive pH-response release characteristics in the release system.Cytotoxicity test showed that ZIF-8/DOX composites only showed strong toxicity to cancer cells,but ZIF-8 material was compatible with cells and low toxicity.ZIF-8 nanobelts also are proved as a biomimetic enzyme in biocatalytic reactions.The loading of horseradish peroxidase(HRP)was up to47%,and the enzyme activity of HRP@ZIF-8 composite was significantly enhanced.Theseresults indicate that ZIF-8 nanomaterials can be used as an excellent carrier of drugs and biomolecules,and have potential applications in biosensors,biocatalysis,biomedical engineering and other biological fields.