Modification And Marine Drugs Loading Of Natural Halloysite Nanotubes

Halloysite nanotubes,a natural aluminosilicate clay with a one-dimensional tubular porous structure,are superior in specific surface area,making it a potential versatile nanosized scaffold for loading guest molecules.The inner surface of halloysite has a low chemical activity,so guest molecules have weak affinity with the inner surface.In order to improve the chemical activity of halloysite,we use sodium oleate,zwitterionic surfactants and other organics as the modification material and prepared halloysite/hollow iron nanocomposite and quercetin-loaded halloysite nanotube composite.The reflection loss properties of the nanocomposites and drug release properties of the antioxidant were studied.The halloysite/hollow iron nanocomposite is a kind of catalytic material with magnetic recovery performance.TEM analysis showed that hollow-core iron was mainly load in the outside surface of HNTs.Due to the absence of oxygen atoms in the reduction process,the center of the iron particles is hollow,with a particle size 25-35 nm and a hollow particle diameter 12-20 nm.With the increasing of aging time,the proportion of hollow iron nanoparticles decreases,while that of solid nanoparticles increases.The hollow iron nanoparticles showed much higher remnant magnetization and coercivity values than the solid ones,and accordingly exhibited higher microwave absorption performance.The maximum RL values and bandwidth of RL<-5 dB of the nanocomposite achieved-10.5 dB and 2.4 GHz,respectively.With advantages of magnetic separation,catalytic degradation capacity of iron nanoparticles,and large adsorption volume of halloysite nanotubes,the prepared HIH nanocomposite was negatively charged and show potential applications in the treatment of marine organic wastewater and heavy metal ions.Marine drugs also play crucial role in the management of marine environment.The halloysite modified by surfactant can successfully overcome the capillary resistance of the nanotubes and adsorb the quercetin molecules into the halloysite lumen without vacuum circulation.The modified halloysite can adsorb quercetin molecules on the inner and outer surfaces of the halloysite,which makes full use of the large specific surface area of halloysite and increases the attachment sites of active guest molecules.Drug release experiments showed that(3-Lauramidopropyl)dimethyl betaine modified halloysite could achieve the requirements of controlled release.It's release period reach 480 h and the release curve can be fitted by first-order kinetics equation,which completely overcome the initial rapid release of quercetin.Meanwhile,the aging temperature of the modified halloysite can effectively promote the grafting reaction between the organic reagents and halloysite,which is favorable for the improvement of affinity between the drugs and the halloysite surface and the optimization of the quercetin release performance in the drug carrier.Compared with previous studies,the prepared halloysite/hollow iron nanocomposite is a magnetic adsorbent with the advantage of excellent performance,simple preparation process,abundant raw materials and no biological toxicity.It can be reused in the treatment of marine organic wastewater and heavy metal ions.The prepared quercetin-loaded halloysite nanotube has excellent adsorption activity on the drug molecules and the release period of drug is 20 times that of the common drug carriers,which is cheap and easy to be obtained and can be effectively used for the long-term treatment of marine algae pollution.Two kinds of composite materials expand the application prospect of halloysite in marine pollution.