Study On Iron,Cobalt Catalyzed Oxidative Pavarov Reaction

This paper is divided into two parts.The first part mainly introduces the research progress of iron-catalyzed cross-coupling reaction.The second part describes the new developed iron or cobalt catalyzed oxidative Povarov reactions.I.A novel iron-catalyzed dual-oxidative dehydrogenative(DOD)tandem annulation of glycine derivatives with tetrahydrofurans(THFs)for the synthesis of high value quinoline fused lactones has been developed.The reactions were performed under mild reaction conditions.And the use of cheap substrates(glycine derivatives and THF)and an even cheaper simple inorganic iron salt as the catalyst makes this protocol very attractive for potential synthetic applications.II.A simple and efficient cobalt-catalyzed aerobic oxidative dehydrogenative Povarov reaction of tertiary anilines with dihydrofuran has been developed for the synthesis of hexahydrofuro[3,2-c]quinolines.The one-electron-oxidation involved reaction is performed under mild conditions and only requires simple cobalt salts as a catalyst and dioxygen as a terminal oxidant.