The Study On Carbon Dioxide As C1 Resource And Carbon Monoxide As Carbonyl Resource In Organic Synthesis

Constantly consumption of fossil resources leads to an increasing demand for green chemistry and clean energy.One-carbon-chemistry represented by carbon dioxide and carbon monoxide has attracted more and more attention.The introduction of carbon dioxide and carbon monoxide as carbon resource into chemical reactions has become a greener way to construct chemical products.In view of the above background,this thesis carries out related research works and will be categorized into the following three parts:1.This thesis summarized the research background:(1)Research progress on activation and conversion of carbon dioxide(2)Research progress on activation and conversion of carbon monoxide.2.We achieved a catalyst-free methylation of amines using C02.This protocol realized the reduction of C02 and built C-N bond,which provided a simple and new way to perform the methylation reactions on several amines.3.We studied the oxidative carbonylation using CO as a carbonyl source under palladium catalysis.A one-pot method was used to generate 2-quinolinone derivatives from 4-octyne,N,N-dimethylaniline and carbon monoxide.Such derivatives are common heterocyclic structures in many natural products and drug molecules.