The Pollution Characters And Human Exposure Of Organophosphate Surrounding A Chemical Plant In Hebei Province

Since the early use of bromine generation of flame retardants containing polychlorinated biphenyls and polybrominated diphenyl ether be banned or restricted use according the “Stockholm convention”,organic phosphate(OPEs)as its substitute products,the growth of the demand and usage are increased fastly.China,as a major producer of organic phosphate,has set up more than ten organic phosphate factories.OPEs now as a new type of pollutants caused more and more attention from scholars in the world,but still lack of data of point sources(organic phosphate factory)surrounding environment and the human exposure.This study research the environment medium sourrounding a organophosphate factory in hengshui city,hebei province and urine samples from exposed people,using gas chromatography-mass spectrometry(GC-MS)analysis environment medium OPEs and liquid chromatography tandem mass spectrometry(LC/MS/MS)analysis OPEs metabolites in urine,The system researches were carried to quantify the concentration levels,composition profiles and compared the concentration of OPEs metabolism in factory Valley and Urban human.And the research in the early stage of the OPEs factory is very important for the compairsion with the pollution levels after decades since the start of the production of OPEs.the main results were as follows:(1)The main products of the factory are TCEP,TCPP,and there may be a small amount productions of TPP.The TPP concentration in the sediment and water samples near the point source is similar to that of the domestic and foreign literatures.The concentration ranges of the two media are nd-1.48ng/g and 0.9-4.4ng/L respectively.The concentration of TCEP and TCPP in two kinds of medium was significantly higher than that of domestic and foreign research,sediment concentration range TCEP and TCPP were 61.07 and 79380.88 ng/g 277.04 194020.8 ng/g;water samples of TCEP and TCPP concentration range 3021.4 14779.5 ng/L respectively,and 4098.1 to 18470.6 ng/L,High concentration of TCEP in sediment and water samples nearby the factory shows that the two media are affected by the pollution of the point source(OPEs factory).Spatial distribution show that the concentration of TCEP and TCPP in sediment and water samples with other studies and decreased with the increase of distance from point source in the conclusion,this study two kinds of medium TCEP and TCPP rising pollution concentration in lower first and then decreases after trend,and the attenuation rate of pollutants in sediment slightly higher than the attenuation rate of pollution in water sample;In water sample and sediment samples TCEP and composition of TCPP analysis shows that the pollutants in the proportion of two types of environmental media distribution is slightly different,TCPP as the main pollutants in sediments,TCEP as the main pollutants in water samples,may be because the two different kinds of OPEs monomer logkow and the solubility of difference.(2)TCEP,TCPP and TPP can be detected in soil samples around the point-source,and these concentration is far lower than these in the sediment.Three kinds of pollutants concentration range is nd-8.6ng/g,nd-0.51ng/g and nd-0.31 ng/g respectively,speculated that the pulltion point source mainly through the sewage discharge medium impact on the surrounding environment.Compared with domestic and foreign studies,the pollution concentration of OPEs in the surrounding soil is lower than thar in the garbage removal area and rural soils.According to the spatial distribution,Pollution concentration of the wind(south)of OPEs in soil pollution concentration is slightly higher than the wind direction(north),shows that the point sources on surrounding soil environment pollution but still have not caused serious pollution.(3)Similar as the sediment and water,the TCEP and TCPP were detected with high concentration in the bark samples,and the concentration range was 4212.4-9092.3ng/g,1824.6-8878.3ng/g.Also detected the TPP with low oncentration,the concentration range of nd-2.3 ng/g,which can prove the accumulation of plants,also can further deduce the plants absorb the OPEs of dissolved in water through the root system to enrichmention to accumulation.(4)The factory surrounding environment have high concentration of TCEP and but concentration of their mebolism BCEP and BCPP in urine is not high,and it similar with other urban and background human’s urine.,may be because of the different path of expourse.This research attempts to find the relationship of the drinking water and the human exposure,the results show that the factory nearby villagers by the exposure of the drinking water load is small,and the exposed area of OPEs content in drinking water cause cancer to human body and the lower the risk of cancer.