Study On Synthesis,Crystal Structure,Spectral Properties And Density Functional Theory Of 1,8-Naphthyridine Derivatives

1,8-naphthyridine derivatives are a class of compounds with excellent optical properties.They are used in fluorescent sensors,bio-medicines such as novel organic nanomaterials,and their good planar rigid structure makes them have good coordination ability.Metal complexes can be synthesized by accessing different metals.The 11 novel 1,8-naphthyridine derivatives synthesized in this thesis use 2,6-diaminopyridine as raw materials to synthesize spectral properties by synthesizing a series of compounds by introducing different groups to prepare fluorescent probes for identifying metal ions.The changes,especially the access to metal fluoroboron,make the study of naphthyridines more comprehensive.The main results are:1.Six new 1,8-naphthidine compounds(A1,A2,A3,A4,A5,A6)and five new 1,8-naphthidine fluoroboron compounds(B1,B2,B3,B4,B5)were synthesized.The structure of the 11 novel compounds in different solvents was determined by nuclear magnetic resonance,mass spectrometry and infrared spectroscopy.2.To explore the performance of 11 novel compounds in ion recognition fluorescent probes,it was found that(A1,A2,A5,B3,B5)have potential as ion recognition fluorescent probes,which proves that these compounds have excellent fluorescent probe performance.The optical properties of 11 compounds after the addition of acid were studied to demonstrate that the compounds are a class of compounds that are sensitive to acid.3.Crystals of three novel 1,8-naphthyridine compounds were cultured,and their structures were further confirmed by an X-ray single crystal diffractometer in combination with nuclear magnetic data.4.Based on the density functional theory,the theoretical spectra of eight compounds were obtained by theoretical calculation and compared with experimental data,revealing the influence of substituents on molecular orbital energy.