Degradation Of Antibiotics From Wastewater And Fermentation Residues By Gamma Irradiation

Due to the resistance of antibiotics to human health and the ecological environment and the safe disposal of antibiotic fermentation residues,the elimination of antibiotics from aqueous solutions and solid bacterial residues has become an urgent problem to be solved in my country.In this paper,?-lactam antibiotics cephalosporin C(CEP-C)and macrolide antibiotics erythromycin(ERY)were used as representatives to study the removal efficiency of cephalosporins and erythromycin by ionizing radiation and Degradation mechanism,investigated the removal efficiency of antibiotics and the effect of irradiation on the microbial population structure and protein and other nutrients in the bacterial residue,and explored the method of ionization irradiation combined with enhanced strengthening to remove antibiotics and resistance genes.1.?-rays can effectively degrade CEP-C and ERY in aqueous solution,using?-ray irradiation to observe the complete disappearance of antibacterial activity of CEP-C against Escherichia coli and Staphylococcus aureus at 2.5kGy,LC-MS and antibacterial activity The analysis showed that the ionization irradiation destroyed the14-membered ring of ERY and the active site of CEP-C.2.The study compares the heat treatment,ozone oxidation and ionization irradiation at 60 oC and 90 oC.In the removal rate of antibiotic fermentation bacterial sludge,ionizing radiation treatment is greater than heat treatment and ozone oxidation treatment;in terms of removing ARGs,?-ray radiation(74.2%)is much higher than heat treatment(26.9%-37.1%)and ozonation(64.6%);under experimental conditions,the effects of ?-ray irradiation and heat treatment on the content of total COD,polysaccharides and protein in CEPF bacterial residue Not large,and these substances can also be oxidized by ozone,resulting in a significant reduction in total solubility and soluble COD,nutrients and pH.After treatment,the richness and diversity of the community have improved,and the community population has changed significantly.3.?-ray radiation and PMS oxidation technology can reduce antibiotics and ARGs in erythromycin residues.At an adsorption dose of 25-50 kGy and a PMS dose of 50-100 mM,about 49-55% of ERY and more than 96% of ARG were removed in the ?/PMS system,respectively.After ?/PMS treatment,the bacteria associated with ARGs were assigned to Aeromonas in Proteobacteria,and the abundance of unclassified Enterobacteriaceae decreased.Taking into account the processing performance and operating costs,it is recommended to use 25 kGy and 50 mM PMS for EB/PMS processing,the operating cost is about $3.8-6.3/t.