Visible-Light Promoted Hydroxysulfurization Alkoxysulfurization Reaction Of Styrenes And Synthesis Of Alkynylphosphine Oxides Under Catalyst-Free Conditions

Visible-light promoted organic reaction has been attracted more attention from the chemist in recent years;and in most case,these photoreactions were induced by addition of photocatalysts or formation of EDA complex compounds.However,the research work about the photoreactions are occoured without formation of any excited states during the transformation received less attention,therefore,these synthetic tactics has shown more challenging.In this thesis,We developed hydroxysulfurization and alkoxysulfurization of styrenes using a visibe-light synthetic strategy without photocatalyst and oxidant.This method provided the corresponding?-hydroxysulfides and?-alkoxysulfides in good yields with hight regioselectivity.The reaction was tolerated by a wide range of functional groups,and this is the first example of the ArSSAr/CBr₄ reaction system has been introduced into visible-light-promoted organic transformation.Organic phosphine compounds plays an important role in the pharmaceutical and agrochemical industries.The efficient construction of carbon-phosphorus?C-P?chemical bonds is a direct method for obtaining organic phosphine compounds.In the other part of this thesis,we have developed a method of directly constructing carbon-phosphorus?C-P?chemical bonds without catalysts,and have achieved the synthesis of alkynylphosphine oxides under mild and simple reaction conditions.This synthesis method was accomplished in absence of transition-metal catalyst and without complicated reaction conditions.More concretely,the alkynylphosphine oxide was synthesized using bromoalkynes and secondary phosphine oxides as the reaction substrates,and the transformation happened through C-P bond formation in acetic anhydride solution.