Subjects Shedding Causes And Correlation Study:Effect Of Acupuncture And Clomiphene Citrate On Live Birth In Infertile Women With PCOS

Objective:Analysis of "acupuncture affects women live birth rates combined clomiphene lot ovary syndrome:a randomized controlled trial of international cooperation" referred to research the reasons(PCOSAct project)in subjects off and related factors,from the subject's compliance management angle analysis of the project,identify gaps for future reference RCR clinical trials in subjects management.Methods:1.Off from the case subjects to evaluate the quality of management PCOSAct project.? analysis of the reasons for drop cases and make analysis.? according to the number of people falling off rate,dropout rate,and overall statistics for each sub-centers,respectively,to the statistical comparisons,outcome measures.? analysis of different subjects to compare treatment cycles off ? This project is the number of sub-centers,vast,divided into North and South to compare the dropout rate.? by way of sub-groups in the project management quality management,point of view there is no difference in the subjects fall.2.In clinical trials,the perspective of compliance management PCOSA project summary.Results:1.In this project study,subjects shedding 76 cases,loss rate of 8%to 20%lower than the planning stage to estimate sample size.2.Each sub-center off numbers reported in this study and included the number of subjects in more than 10 percent dropout rate has seven,to compare the center after 21 minutes into the group whether the dropout rate differences.3.It subjects the treatment cycle is divided into the baseline visit and the first treatment cycle 1,2,3,4,points five cycles.The total number of cases in the first treatment cycle 1 and 2 accounted for 57%off the total number of cases falling.These five cycles were compared,P<0.054.Sub-centers of this project is distributed everywhere in China,all the sub-center is divided into North and South,to compare P<0.05,off north and south of the subjects have differences5.In the present study is divided into three phases of the project management team management,comparison shedding three groups,P<0.05.Conclusions:(1)In this project study,subjects shedding 76 cases,loss rate of 8%to 20%lower than the planning stage to estimate sample size.(2)According to a comprehensive analysis of case information subjects shedding,shedding causes and subjects from the perspective of the reasons summarized shedding,shedding correlation analysis for future scientific research in the subject compliance management,providing reference.(3)Through the sub-centers across the country were shedding the comparison difference,so the project team on the subject of surveillance should be more reference standard operating procedures,increased monitoring frequency,in the management of research staff to continue stronger.