The Assoeiation Between Syndrome Differentiation Of TCM And Insulin Resistance In Type 2 Diabetes Mellitus With Non-alcoholie Fatty Liver Disease And Analysis Of Correlated Risk Factors

Objective To study the assoeiation between syndrome differentiation of traditional Chinese medicine and insulin resistanee(IR)intype 2 diabetes mellitus(T2DM)with non-alcoholic fatty liver disease(NAFLD)and To explore the correlated risk factors associated with non-alcoholic fatty liver.Mathods According to WHO diagnostic criterion of western medicine and criterion of exclucive case,179 patients of T2DM with NAFLD were seleeted and divided into four groups,and 30 cases of T2DM without NAFLD patients were selected as the compare group.Height,bodyweightFPG,FINS,HDL-C,HbAlc,LDL-C,AST,ALT,TG,CHOLwere Measured,then calculat to BMI and insulin resistance(IR)index and discusses the differences of the different TCM syndrome types of IR,There lationshiP between the indexes andsyndrome differentiation of TCM were analyzed.By unconditional Logistic regression for T2DM and NAFLD disease risk factor analysis.Rsesults ? In patients with T2DM and NAFLD disease of TCM,DHS was maximum,SBS was minmum,next was QYS,then was YDEHS.? In patients with T2DM and NAFLD disease of TCM of age stratification,found that in most patients with50 to 70 years old,the second is 30-50 years old,the difference was statistically significant((P<0.05));For each card type course of stratified found that course for 5-10 years the number of cases,most of course>10 years reduced number of cases,the difference was statistically significant(P<0.05).? T2DM and NAFLD is different between the IR syndrome group comparison.is in turn:type of DHS>type of QYS.>type of SBS>type of YDEHS.Comparison between groups:type of DHS with type of SBS and type of YDEHS has statistically significant different(P<0.05);type of QYS with type of YDEHS has statistically significant different(P<0.05);Between groups in terms of the rest is meaningless(P>0.05).?TG?ALT?LDL-C?FBG?FINS?HOMA-IR?BMI?HbAlc of T2DM with NAFLD were also high than those of T2DM without NAFLD group(P<0.05).?BMI,TG is the risk factors of the T2DM with NAFLD.Conclusions ? T2DM and NAFLD in patients with TCM syndrome type byYin deficiency heat from hot and humid embodiment and qi and Yin deficiency and blood stasis resistance development.? For combined T2DM patients with NAFLD,sugar,lipid metabolic disorder is more apparent.?In patients with T2DM and NAFLD mainly concentrated in the 30 to 50 years old.between 5-10 years the largest number of course of the disease.?IR to DHS in the TCM dialectical classification model is most obvious;Along with theprogressionofinsulinresistancehasadownwardtrend.(5)BMI and TG make a key role in T2DM and NAFLD patients.